5 Classes of Immunoglobulins

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5 Terms

1
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IgA

agglutination and neutralization

monomer

mucous membrane secretions, including milk

10-15% in serum

2
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IgD

Unkown

monomer

B cell surface

less than 1%

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IgE

Triggers release of histamines from basophils and mast cells 

monomer 

serum, mast cell surface

less than 1% in serum 

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IgG

Complement activation, agglutination, opsonization, and neutralization; crosses placenta protect fetus 

monomer 

serum, intercellular fluid 

80% in serum 

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IgM

complement activation, agglutination and neutralization

pentamer

serum

5-10% in serum