Ch 12 Infectious disease

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Description and Tags

Biology

17 Terms

1
Disease described as infectious (communicable) if
caused by invasion by a pathogen and can be transmitted from one host to another
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2
pathogen
infectious agent that cause disease
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3
host
organism infected with a pathogen
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4
signs and symptoms result from
damage to tissues and organs of the host
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5
Most common pathogen groups
Viruses (influenza, Ross River virus disease)

bacteria (tuberculosis, tetanus)

fungi (chytridiomycosis)

protists (malaria, phytophthora dieback)
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6
Transmission
passing of an infectious disease from an infected host to another individual
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7
Contagious
easily transmitted by close contact with an infected organism or their secretions (body fluids)
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8
Zoonotic diseases
infectious disease - transmitted from one vertebrate group to another

e.g. avian (bird) or swine (pig) influenza virus can infect humans via direct contact, close contact and indirect contact
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9
Ways of transmission
Direct contact with infected host’s saliva, mucus, faeces, blood or urine when handling bird or scratched

Close contact - airborne and inhaled (bird shake feathers)

Indirect contact - susceptible host comes into contact with area - infected animals live or roam - surfaces or objects contaminated
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10
virulence
severity of the disease it causes

\-help pathogen invade a host, cause disease + evade host defences
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11
susceptibility
likelihood of developing a disease;

\-if high = ability to resist disease ↓

\-depend on age, state of health, immune system
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12
symptoms
effects the pathogen has on the body of the host
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13
incubation period

time between infection and onset of symptoms

-occur due to:

  • pathogen dividing many times to reach numbers sufficient to cause disease

  • take time to reach target tissues susceptible to particular pathogen

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14
Disease often contagious before onset of symptoms
\-pathogen can be passed on before the person even knows they have it

\-incubation period = adaptation of the pathogen, allow it to be transmitted before host incapacitated by symptoms
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15
Virus
\-non-cellular pathogens = no metabolic processes

\-consists one or more strands of nucleic acid (RNA/DNA) inside protein coat (capsid)

\-microscopic = 30-300nm

\-neither prokaryotic or eukaryotic

\-obligate parasite = cannot function outside a host cell

\-limited to infecting a specific host cell or organism = virus recognise and bind to receptors on cells (adenovirus infects epithelial cell in upper respiratory tract - cold)

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Example of diseases caused by viruses
Ross River disease

COVID-19

influenza
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17
Viral replication in eukaryotic host
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robot