Ocular III

What is the most common eyelid tumor from the eye in dogs

Meibomian gland adenomas/epitheliomas/adenocarcinomas

What is another eyelid and conjunctival tumor in dog

Melanomas, papillomas, squamous Cell carcinoma, histiocytoma, MCT

What is eyelid and conjunctival tumor of Cat

SCC of eyelid/conjunctiva (linked to UV light especially in white cats)

Eyelid and conjunctival tumor of Large animal

SCC most common in cattle, horse, sheep associated with UV exposure and lack periocular pigment 

Meibomian gland tumors occur where

arise at eyelid margin

Meibomian gland tumors account for what percent eyelid tumors

70%

Meibomian gland tumors grossly

pink-gray or black pigmented

often traumatized and covered with crust 

Adenocarcinoma of Lacrimal/ salivary gland occurs where

From zygomatic salivary gland in inferior orbit

From lacrimal gland in superior orbit

Corneal and Scleral Tumors are rare or common primarily

rare

SCC may extend where

in which species

onto cornea from conjunctiva

horses and cattle

Limbial (epibulbar)melanocytoma in dogs

malignant or benign

Benign but may reoccur

Retinal and Optic Nerve tumors are rare or common in domestic animals?

Rare

Secondary infiltration by lymphoma or metastic neoplasia more common than primary tumors

Orbital tumors

Local or diffuse?

May cause what?

Locally invasive: osteosarcoma, fibrosarcoma, meningioma

Cause exophthalomas, strabismus, impaired globe mobility 

Secondary metastases possible

Intraocular tumors

Uveal melanomas

Dog

Cat

Horse

Dogs-benign melanocytoma, slow progression

Cats-more malignant can invade orbit and metastasize especially diffuse iris melanoma FDIM

Horse-uveal melanocytic tumors may be incidental

Iridocillary adenoma/adenocarcinoma

Arise from ciliary body epithelium

Lymphoma

may infiltrate uvea secondarily as part pf systemic disease

Medulloepithelioma

Rare congenital intraocular neoplasm

Most common intraocular neoplasm in dog

Uveal melanocyte tumor

Most common primary intraocular tumor in cat

Feline diffuse iris melanoma

Canine Uveal melanocytoma/melanoma origin

Behavior

arises from melanocytes of iris, ciliary body, choroid

Behavior- most uveal melanocytic tumor benign

Malignant less common show local invasiveness but low metastic rate

Clinical Signs of canine uveal melanocytoma

Pigmented mass in anterior uvea, dyscoria, secondary glaucoma, hyphema

Treatment Canine uveal melanocytoma/melanoma

Enucleation is vision lost or glaucoma develops; prognosis generally good due to low metastatic risk

Ocular melanosis

non neoplastic acquired pigmentary condition of eye in dogs, not tumor but characterized by progressive melanin deposition in ocular tissue increased melanocyte activity and pigment production in iris, cilliary body, sclera

Which dogs are predisposed to ocular melanosis

Carin terriers, Labs, Boxers

FDIM Feline diffuse iridal melanoma is what percent of all ocular neoplasms in cats

50%

How does FDIM usually arise

unilaterally on anterior surface of iris in middle aged cats

FDIM Feline Diffuse Iridal Melanoma grossly

Foci large and coalesce leading to diffuse infiltration of iris that may infiltrate iridocorneal angle(secondary glaucoma) ciliary body and sclera

Feline Diffuse Iridal Melanoma differential diagnosis

Hyperpigmentation(melanosis) iridociliary cysts, amelanotic forms, pleomorphic lymphoma and histiocytic sarcoma

What is the second most common intraocular tumors of cats

Uveal lymphoma

Average age for a cat with uveal lymphoma

10 years

Uveal lymphoma may arise from

B or T cells

may be part of systemic lymphoma

What is the 3rd most common intraocular tumor in cats

Feline posttraumatic ocular sarcoma

Average age of cats with FPTOS

11 years

Causes of Feline posttraumatic ocular sarcoma

history trauma, chronic uveitis, intravitreal application of gentamicin

Iridociliar adenoma/ Carcinoma affects what percent of cats

3.9% of ocular tumors in cats

Average age of cat with irdociliar adenoma/carcinoma

9 years

Iridociliar adenoma/carcinoma characterisitcs in cat

Fill posterior chamber of eye

infiltrate iris, ciliary body, rarely sclera

pigmentation rare

contain cysts

may contain metaplastic bone