VIBS 222: Endocrine Disruptors

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20 Terms

1
What was DDT used for?
kill malaria and typhus vectors: mosquitoes
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2
Which book got DDT banned?
Silent Spring by Rachel Carson
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3
What were some problems with DDT in ANIMALS?

abnormal genitalia in alligators

decline in bald eagle population

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4
What were some problems with DDT in HUMANS?

low birth weight

small skull circumference

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5
What is DBP used for?

automotive parts

beverage containers

medical supplies

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6
What is the MOST abundant synthetic chemical in the environment?
pthalates
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7
What did INTRAUTERINE DBP treatment cause in male rabbits?

decreased test levels

increase in abnormal sperm

carcinoma in situs

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8
What is DEHP and MEHP used for?

production of PVC plastics

medical and food packages

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9
What is DEHP to MALES?

testicular toxicant

sertoli cell toxicant in vivo

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10
What is DEHP to FEMALES?

decreased estradiol levels

no ovulations

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11
What are the HEAVY metals?

mercury

lead

cadmium

manganese

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12
What was CD linked to in MALES?
disrupted prostate development and prostate cancer
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13
What are some ways to be exposed to CADMIUM?

welding

cigarette smoking

fish consumption

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14
What does CIGARETTE smoke contain?

> 4000 chemical compounds

43 carcinogens

> 300 PAHs

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15
How many people die from CIGARETTES/2ND HAND SMOKE yearly?

> 480,000 from smoking

> 41,000 from 2nd hand

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16
What is the #1 PREVENTABLE cause of death in the U.S?
smoking
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17
What are the risks of smoking for WOMEN?

60% higher risk for infertility

affected success for IVF

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18
What are the risks of smoking for MEN?

reduced sperm quality, count, motility

higher rates of infertility

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19
What are PAHs?
chemicals formed during incomplete burning of organic substances
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20
What are some EXAMPLES of polycyclic aromatic hydrocarbons?

napthalene

benzopyrene

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