Genomics & Proteomics Lecture Review

Flashcards created to test knowledge on key concepts covered in the lecture about Genomics and Proteomics.

What is functional genomics?

The study of genomic functions and their roles in cellular, organismal, and evolutionary processes.

What is RNAi?

RNA interference, a biological process where RNA molecules inhibit gene expression by destroying specific mRNA molecules.

How does C. elegans assist in genomic studies?

C. elegans is a model organism used for genome-wide RNA interference screens to identify genes involved in biological processes such as fat storage.

What are the potential applications of RNAi in drug design?

RNAi can be used to design new drugs targeting infectious diseases, such as anthelmintics.

What is the Human Genome size?

Approximately 3200 Mb.

What percentage of human genes is unique?

About 13,000 genes are unique, while around 50% of the remainder have a function inferred from homology analysis.

What is proteomics?

The study of the complete set of proteins within a cell or organism and their interactions.

What is the Yeast-2-Hybrid system?

A method used to study protein-protein interactions by introducing 'bait' and 'prey' constructs into yeast cells.

What is transcriptomics?

The study of the complete set of RNA transcripts produced in a cell or organism under certain conditions.

What are the components of the Human Interactome?

Identified with ~93,000 protein interactions through methods like Yeast-2-Hybrid and mass spectrometry.