Campylobacter

Gram?

negative

Motility?

motile; UNsheathed flagella

Growth conditions

microaerobe, most will grow at 42C

Special stuff

does NOT have urease, sensitive to nalidixic acid, form coccoid bodies

Transmission?

fecal-oral

Most common cause of enteritis?

C. jejuni

Most common cause of extraintestinal infections?

C. fetus fetus

Virulence factors

flagella, cytolethal distending toxin

What does the cytolethal distending toxin do?

causes DNA breakage

Selective media?

blaser’s, skirrow

C. jejuni infections in humans?

inflammation of basolateral side of intestinal epi cells, induces diarrhea

Extraintestinal infections?

bacteremia (transient, secondary, chronic), endocarditis, meningoencephalitis

What is Guillain-Barre syndrome?

immune system attacks peripheral nervous system

What animals are affected by vibrionic abortion?

cattle, sheep

What is transient bacteremia?

short period of time in bloodstream

What is secondary bacteremia?

spreads from initial source (localized) to another site

What is chronic bacteremia?

persistent infection in bloodstream