W3 - Alveoli

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4 Terms

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Alveoli

  • ~300 million alveoli total surface area is 150m2

  • dense capillary supply

  • site of gas exchange

  • thin barrier for gas exchange

<ul><li><p>~300 million alveoli total surface area is 150m<sup>2</sup></p></li><li><p>dense capillary supply</p></li><li><p>site of gas exchange</p></li><li><p>thin barrier for gas exchange</p></li></ul><p></p>
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Structure of alveoli

  • formed from squamous type I alveolar epithelial cells → comprise of the respiratory membrane where they contract surrounding capillaries

  • scattered type II cells - secrete surfactant (prevents alveolar collapse)

  • alveolar macrophages monitor internal alveolar surfaces

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respiratory membrane

  • thin air-blood barrier (0.5um wide)

  • liquid coating (prevents dehydration)

  • composed of:

    • single layer of squamous alveolar epithelium (type I cells)

    • fused basement membrane

    • pulmonary capillary (endothelial cells)

  • site of gas exchange (via simple diffusion)

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