Lecture 3b: Acid dissociation constant (pKa)
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9 Terms
What does pKa measure?
The acid strength of a substance (how easily it donates a proton)
What does a low pKa indicate?
A strong acid — more likely to donate a proton.
What does a high pKa indicate?
A weak acid — less likely to donate a proton.
What is the relationship between base strength and the pKa of its conjugate acid?
Strong base → weak conjugate acid → high pKa
Weak base → strong conjugate acid → low pKa
Why does a strong base have a high pKa?
Because its conjugate acid is very weak and does not easily donate a proton.
Why does a weak base have a low pKa?
Its conjugate acid is stronger and donates a proton more readily.
What is an amphoteric compound?
A substance that can act as both an acid and a base depending on the environment.
What structural feature makes a molecule amphoteric?
The presence of both acidic and basic functional groups
How do amphoteric compounds behave with strong acids and strong bases?
With strong acids → act as a base
With strong bases → act as an acid
Note 
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