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Metabolism
Is the sum total of all the chemical reactions that go on in living cells.
Anabolism
Build more complex compounds
Catabolism
Break down compounds further
What is the major energy carrier in most cells?
ATP
What is glycolysis?
(Glucose Breakdown) (Glu—>Pry)
Reversible
Anaerobic
Produces ATP
Catabolism of Glucose?
Glucose to Pyruvate to Acetyl CoA to TCA Cycle to ETC
Catabolism of Lipids?
Glycerol to Pyruvate; Fatty Acids to Acetyl CoA
Catabolism of Proteins?
Amino Acids to Pyruvate, Acetyl CoA, or TCA Cycle
Can pyruvate be converted back to glucose?
Yes, through gluconeogenesis, pyruvate can be converted back to glucose in the liver.
Can acetyl CoA be converted back to glucose?
No, acetyl CoA cannot be converted back to glucose due to the irreversible steps in the citric acid cycle.
Can fatty acids be used to make glucose?
No, fatty acids cannot be converted to glucose because they are metabolized exclusively into acetyl CoA.
Anaerobic vs. Aerobic
Anaerobic: Without Oxygen
Aerobic: With Oxygen
Which nutrients, in excess, can be stored as fat?
Carbohydrates, proteins, and fats
What happens during fasting?
Blood nutrients for energy 1st, then to glycogen storage, that fat and protein
What are factors that influence the ease and difficulty of weight loss/gain?
hormones, enzymes, muscle fiber type, brain perceptions
Hunger
the physiological drive for food that initiates food-seeking behavior
Satiation
Feeling of fullness that occurs during a meal and halts eating.
Satiety
The feeling of fullness that occurs after a meal and inhibits eating until the next meal
What is the reasonable rate of weight loss?
-½ to 2 pounds per week
-10% body weight in 6 months
What is the Thermic Effect of Food?
10% of total kcals
Physical Activity?
30-50% of total kcals
Body Mass Index-definition, indicator of body composition?
classifications for healthy weight, underweight, obese
What are the factors that affect Basal Metabolic Rate (BMR)?
Age, hight, growth, body composition, fever, stresses, environmental temperature, fasting/starvation, malnutrition, hormones, smoking, caffeine, sleep.
Ideal Body Fat% for Men and Women?
-Men: less than 22%
-Women: less than 32%
Android v.s Gynoid Obesity
Android vs. Gynoid Obesity:
Android: “apple-shaped”:
Fat is stored around the organs of the abdomen
Associated with increased risks of HD, stroke, DM, HTN
Gynoid: “pear-shaped”:
Fat is stored around the hips and thighs
Associated with less risks
What are the waist circumference associated with risks for men and women
Men: >40 inches, Women: >35 inches
What are the waist-to-hip ratio associated with risks for men and women
≥ 0.8 women
≥ 0.9 men
Energy "out"/components of energy expenditure) include?
Basal Metabolic Rate (BMR), Thermic Effect of Food (TEF), and Physical Activity (plus NEAT).
What are the recommendations for physical activity?
most days per week or five days per week for 1 hour per day
What is the fad diet?
promotes quick weight loss
What is the percentage of the population that is overweight or obese?
70% of Americans are obese
40% of people in Arkansas are obese
What are the reasonable weight gain concepts?
Include juice and milk between meals, include nutrient-dense and energy-dense foods, include exercise and weight resistance training
Best approach to weight loss=
diet + physical activity increase energy expenditure and decrease energy intake
What is the minimum # of kcals necessary to ensure nutritional adequacy?
1200
What is the Female Athlete Triad?
Eating Disorder, Amenorrhea, Osteoporosis
Eating Disorder
Restrictive dieting
Overexercising
Weight loss
Lack of Body fat
Amenorrhea
Characterized by low blood estrogen, infertility, and often bone losses
Diminished hormones
Osteroporosis
Loss of bone calcium