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Based on AP Course Guide
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Neurons
Nerve Cells, building blocks of the nervous system, many different types
Glial Cells
Helper cells that send and receive chemical signals to and from each other and neurons
Sensory neuron
Involved in sensation/senses, different for each sense, respond to non-chemical stimulation, send inward signals that arrive @ brain
Motor Neurons
Involved in reflexes and movement, connected to all of our muscles, can react to involuntary and voluntary signals, send signals that exit brain
Interneuron
Sends signals between sensory and motor neurons
Receptor site
Receives a sensation (sensory neuron)
Jobs of neurons
receive, carry, and send messages
Soma
Cell body, includes nucleus, keeps nucleus healthy
Dendrites
Receive signals entering a neuron
Axon
Tube that action potentials go down
Myelin Sheath
A fatty substance that protects and insulates axons
Axon Terminal
The end of the neuron, where information is passed to other dendrites
Synaptic Gap
The place where neurotransmitters cross and lock into the dendrite of the postsynaptic neuron
Action Potential
The electric impulse that travels down the length of an axon
Excitatory Neurotransmitters
Make the next neuron more likely to fire
Inhibitory Neurotransmitters
Make the next neuron less likely to fire
Resting Potential
The point at which a neuron is not active (polarized)
Firing Threshold
The certain threshold at which a neuron will fire
All or None Law
Once at threshold, the neuron will fire and at the same intensity each time
Depolarization
The point during the action potential when the neuron’s charge becomes positive
Refractory Period
A brief period where the neuron can’t fire again
Reuptake
The sending neuron recollects neurotransmitters
Neurotransmitters
Chemical messengers of the nervous sytem
Glutamate
Most abundant excitatory neurotransmitters, enhances learning and memory by strengthening synaptic connections
GABA
Most abundant inhibitory neurotransmitter that is associated with various anxiety disorders
Acetylcholine
Found in both central and peripheral nervous systems, involved in movement, learning, and memory
Dopamine
Linked to pleasurable and rewarding activities, as well as movement, attention, and learning
Endorphins
Associated with pain reduction, can be stimulated by prolonged exercise
Epinephrine (Adrenaline)
Both a neurotransmitter and hormone, boosts energy and is involved in fight or flight responses
Norepinephrine (Noradrenaline)
Neurotransmitter involved in arousal, alertness, and heightened sensitivity to what is going on around you, heavily associated with sleep wake cycle
Serotonin
Neurotransmitter that plays a role in mood, appetite, and sleep
Agonists
Bind with the neurotransmitter at the synapse to increase neural firing
Antagonists
Binds with a neurotransmitter in a way that decreases neural firing by blocking the neurotransmitter at the synapse
Heroin
An agonist for endorphins
Nicotine
An agonist for acetylcholine, stimulates skeletal muscles and causes increased heart rate
Black Widow Venom
An agonist for acetylcholine, toxin that can lead to death
Reuptake Inhibitors
Drug or chemical introduced at synapse that blocks reuptake channels
Prozac
Inhibits reuptake of serotonin, flooding the synapse with serotonin
Cocaine
Inhibits reuptake of dopamine, flooding the synapse with dopamine (agonist for dopamine), while elevating serotonin and norepinephrine, stimulant, intense euphoria, alertness, heightened self confidence
Botox
A toxin that freezes muscles from firing so wrinkles don’t form, antagonist for acetylcholine
Thorazine
An early drug for schizophrenia that is an antagonist for dopamine
Psychoactive drugs
Alter mental states and activate dopamine-producing neurons in the brain’s reward system
Tolerance
Needing increasing amounts of the drug to create the desired effect
Blood-Brain Barrier
A semi-permeable barrier that allows some chemicals to pass into the brain but prevents other from passing into the brain, all psychoactive drugs can pass this barried
Depressants
Slow or inhibit CNS functions, relieve anxiety and create drowsiness, combining different ones can be deadly
Opioids
Agonists for endorphins, incredibly effective and create powerful withdrawal symptoms
Stimulants
Activate sympathetic nervous system functions, increase brain activity and mental alertness
Hallucinogens
Create sensory and perceptual distortions, alter mood, and affect thinking
Alcohol
Agonist for GABA, net slowing effect on CNS functions
Caffeine
Promote wakefulness, mental alertness, and faster thought processes by stimulating dopamine release, antagonist for adenosine, blocks sleep-inducing effects
THC
Mild hallucinogen, produces sense of well-being, mild euphoria, dreamy state of relaxation, in marijuana, interferes with muscle coordination, learning, memory, and overall cognitive functions, various therapeutic uses