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endomysium
layer of connective tissue surrounding each skeletal muscle fiber
fascicle
small bundle of muscle fibers
perimysium
sheath of connective tissue that encloses a bundle of skeletal muscle fibers or a fascicle
epimysium
outer layer of connective tissue surrounding a skeletal muscle
tendon
cordlike or bandlike mass of dense connective tissue that connects a muscle to a bone
aponeurosis
sheet of connective tissue that attaches muscles to bone, skin, and other muscles
fascia
the most superficial layer and is continuous with the epimysium and serves to separate individuals muscles
compartment
the space that contains a particular group of muscles, blood vessels, and nerves all tightly enclosed by fascia
deep fascia
the portion of the network that surrounds the muscles
subcutaneous fascia
lies just beneath the skin, forming the subcutaneous layer
myofibril
any of the thread-like bundles of filaments in striated muscle cells
sarcolemma
a tubular sheath that encase and defines each muscle fiber, forming a barrier between extracellular and intracellular compartments
sarcoplasmic reticulum
membranous network of channels and tubules in a muscle fiber, corresponding to the smooth endoplasmic reticulum of other cells.
thin and thick filaments
structures containing the contractile proteins actin and myosin
location is intercellular
myosin
protein that, with actin, forms the filament that interact to contract muscle fibers
actin
protein in a muscle fiber that forms the thin filaments that slide between filaments of the protein myosin, shortening the muscle fibers
sarcomere
structural and functional unit of a myofibril
titin
protein that attaches myosin filaments to z lines in muscle
troponin
protein that regulates muscle contraction by altering the position of tropomyosin
tropomyosin
protein that blocks muscle contraction until its position is modified by troponin when calcium ions are present
transverse tubules
membranous channel that extends deep into the cell from a muscle fiber membrane. extensions of the sarcolemma into the sarcoplasm and contain extracellular fluid
I band
(the light bands) composed of thin actin filaments held by direct attachments to structures
Z bands
appear in the center of the I bands
A bands
(the dark bands) composed of thick myosin filaments overlapping thin actin filaments. Also a slightly lighter central region
M line
consists of proteins that help hold the thick filaments in place
striation
the visible alternating light and dark bands or stripes that characterize skeletal and cardiac muscle tissue, resulting from the organized arrangement of contractile proteins within the muscle fibers
troponin-tropomyosin complex
a regulatory protein system on the thin filaments (actin) of muscle cells, crucial for calcium-dependent regulation of muscle contraction
sarcoplasm
the cytoplasm containing nuclei, mitochondria, and myofibrils
cisterna
enlarged portion of the sarcoplasmic reticulum near the actin and myosin filaments of a muscle fiber
synapse
functional connection between the axon of one neuron and the dendrite or cell body of another neuron or the membrane of another cell type
neurotransmitter
chemical that an axon secretes, into a synapse, that stimulates or inhibits an effector or other neuron
motor neuron
neuron that conducts impulses from the central nervous system to an effector
synaptic cleft
a narrow extracellular space between the cells at a synapse
acetylcholine
type of neurotransmitter, which is a biochemical secreted into the synaptic clefts at the axon ends of neurons. diffuses across synaptic cleft
sliding filament model
muscles shorten when the thin(actin) and thick (myosin) filaments slide past each other, pulling on the muscle ends
action potential
sequence of electrical changes in part of a nerve cell or muscle cell exposed to a stimulus that exceeds threshold
myoglobin
oxygen-storing pigment in muscle tissue
creatine phosphate
molecule in muscle that stores energy
acetylcholinesterase
enzyme that catalyzes breakdown of acetylcholine
lactic acid threshold
when skeletal muscles are used more strenuously, these systems may not be able to supply enough oxygen to sustain the aerobic reactions of cellular respiration. Under these conditions muscles maybe limited to the anaerobic reactions to produce ATP, this shift in metabolism is referred to as
NMJ (neuro-muscular junction)
is a chemical synapse between a motor neuron and a muscle fiber