Amino acids, peptides and proteins 2

Proteins perform most of the chemistry of life and many other functions so they are..

Molecular machines

What are the 7 different functions of proteins and what do they do?

What do proteins bind to in order to mediate function?

Range of biomolecules and small molecules

What interactions are involved in chemical events of protein interactions?

The same interactions involved in folding

In order for a protein interaction to occur what must the protein and it’s binding partner be in?

The correct orientation

4 key things about binding specificity

What is meant by protein dynamics?

Proteins are dynamic and so are their interactions so they are in constant motion, sometimes changing between distinct conformations. Protein interactions can induce structural changes

Protein dysfunction

Drug- protein interactions

Case study DPP-4