Unit 3: Receptor locations/effects (chart)

muscarinic

CNS (mediate ACh effects in brain)

muscarinic

visceral/bronchiole smooth m (contract)

muscarinic

cardiac m (decrease HR)

muscarinic

exocrine glands (salivary, intestinal, lacrimal) (increase secretion)

muscarinic

sweat gland (increase secretion)

alpha 1

vascular smooth m (contract)

alpha 1

intestinal smooth m (relax)

alpha 1

radial m iris (contract)

alpha 1

ureters (increase motility)

alpha 1

urinary sphincter (contract)

alpha 1

spleen capsule (contract)

alpha 2

CNS inhibitory synapses (decrease symp d/c from CNS)

alpha 2

presynaptic terminal at peripheral adrenergic synapses (decrease NE release)

alpha 2

GI tract (decrease motility/secretion)

alpha 2

pancreatic islet cells (decrease insulin secretion)

alpha 2

some arterioles (skel m, liver, kidneys) (vasoconstrict)

beta 1

cardiac m (increase HR/contract)

beta 1

kidney (increase renin secretion)

beta 1

fat cells (increased lipolysis)

beta 2

bronchiole smooth m (relax (dilate))

beta 2

some arterioles (skel m, liver) (vasodilate)

beta 2

GI smooth m (decrease motility)

beta 2

skel m/liver cells (increase cell metabolism)

beta 2

uterus (relax)

beta 2

gallbladder (relax)

beta 3

fat cells (increase lipolysis)

beta 3

bladder (decrease detrusor m contract)

beta 3

heart (decrease contract)