autonomic nervous system

alpha-1 targets

blood vessels

neurotransmitter for SNS preganglionic

ACh

neurotransmitter for SNS postganglionic

NE

where are nicotinic receptors located

skeletal muscle

where are muscarinic receptors found

smooth muscle and heart

alpha-2 targets

CNS effects

beta-1 targets

heart and kidneys

beta-2 targets

lungs

alpha-1 stimulates (agonist)

vasoconstriction

alpha-1 blocks (antagonist)

vasodialation

what is alpha-1 agonist used for

nasal congestion

what is alpha-1 antagonist used for

HTN, BPH

alpha-2 antagonist stimulates

CNS activation

beta-1 when targeting heart stimulates (agonist)

increase HR and force of contraction

beta-1 when targeting kidneys stimulates (agonist)

increase renin secretion

beta-blockers used for

a-fib

side effects anticholinergics

• cant see

• cant pee

• cant spit

• cant shit

what are anticholinergics used for

COPD