Subcutaneous Mycoses

Which affect subcutaneous and cutaneous tissues of the hands and feet?

Chromoblastomycosis

face, cornea of eye, subcutaneous and cutaneous part of skin, occasionally cerebral and systemic

Phaeohyphomycosis

cutaneous and subcutaneous tissues and adjacent lymphatics that suppurate, ulcerate and drain

Sporotrichosis

subcutaneous and cut. tissues over different parts of body

Lobomycosis

nasal cavities, mucocutaneous tissue - rarely it does effect the vagina, penis, anus, ears, and throat region

Rhinosporidiosis

Where is the mycetoma belt?

Tropical and sub-tropical areas

What do we see in the microscope in case of actinomycetoma:

• Thin branching filaments

  Gram positive

  Acid fast in case of Nocardia

What do we see in the microscope in case of Eumycetoma:

Broad septate hyphae

Mycetoma-Treatment

ketonazole or IV miconazole

Cauliflower shaped lesion:

Chromoblastomycosis

What disease is strictly in dolphins and people in Brazil?

Lobomycosis

Systemic mycosis route of transmission:

• Inhaled

• through break in skin

Which mycoses is dimorphic?

Blastomyces dermititidis

Type of blastomycosis:

1ry(cutaneous-self limiting)

2ry(systemic)

What are the forms of mycosis?

1. Acute pulmonary blastomycosis

2. Chronic pul.. “

3. Disseminated blastomycosis

Which mycosis form is mistaken for carcinoma?

Chronic pulmonary mycosis

*bec it grows in upper lobe

Which blastomycosis is self limiting?

Acute pul.. blast….

Will a sputum sample for blastomycosis grow organism?

No,

There are 3 serological tests used for blastomycosis:

• Immunodiffusion test (precipitin). Fastest

• Complement fixation (CF) test

• Enzyme Immunoassay (EIA).

What is the treatment of mild blastomcosis?

Itraconazole

Treatment of severe blastomycosis:

Amphotericin B

How does Coccidioidomycosis spread?

Through inhalation

Geographic Distribution of Coccidioidomycosis

Southwest of america + mexico

Blastomycosis Geographic Distribution:

South east + South central of america

What disease does Coccidioidomycosis resemble?

Influenza