20 amino acids with pKa

Glycine (Gly/G)

Nonpolar, aliphatic R Groups

pKa: 2.35 (C), 9.78 (N)

Alanine (Ala/A)

Nonpolar, aliphatic R Groups

pKa: 2.35 (C), 9.87 (N)

Proline (Pro/P)

Nonpolar, aliphatic R Groups

pKa: 2 (C), 10.6 (N)

Valine (Val/V)

Nonpolar, aliphatic R Groups

pKa: 2.79 (C), 9.72 (N)

Leucine (Leu/L)

Nonpolar, aliphatic R Groups

pKa: 2.33(C), 9.74(N)

Isoleucine (Ile/I)

Nonpolar, aliphatic R Groups

pKa: 2.32 (C), 9.76 (N)

Methionine (Met/M)

Nonpolar, aliphatic R Groups

pKa: 2.28 (C), 9.21 (N)

Phenylalanine (Phe/F)

Aromatic R groups

pKa: 2.58 (C), 9.24 (N)

Tyrosine (Tyr/Y) (w/ pKa)

Aromatic R groups

pKa: 2.2 (C), 9.11 (N)

side chain pKa: 10

Tryptophan (Trp/W)

Aromatic R groups

pKa: 2.38 (C), 9.39 (N)

Serine (Ser/S)

Polar, uncharged R groups

pKa: 2.21 (C), 9.15 (N)

Threonine (Thr/T)

Polar, uncharged R groups

pKa: 2.09 (C), 9.10 (N)

Cysteine (Cys/C) (w/ pKa)

Polar, uncharged R groups

- pKa: 2.05 (C), 10.25 (N)

- sidechain pKa: 8

Asparagine (Asn/N)

Polar, uncharged R groups

pKa: 2.02 (C), 8.8 (N)

Glutamine (Gln/Q)

Polar, uncharged R groups

pKa: 2.17 (C), 9.13 (N)

Lysine (Lys/K) (w/ pKa)

Positively charged R groups

- pKa: 2.18 (C), 10.53 (N)

- side chain pKa: 10

Arginine (Arg/R) (w/ pKa)

Positively charged R groups

pKa: 2.02 (C), 8.8 (N)

- sidechain pKa: 12.48

Histidine (His/H) (w/ pKa)

Positively charged R groups

- pKa: 1.77 (C), 9.18 (N)

- sidechaine pKa: 6

Aspartate (Asp/D) (w/ pKa)

Negatively charged R groups

- pKa: 2.10 (C), 9.82 (N)

- sidechain pKa: 3.86

Glutamate (Glu/E) (w/ pKa)

Negatively charged R groups

- pKa: 2.10 (C), 9.47 (N)

- sidechain pKa: 4.07