AMINO ACID PKAS AND DELTA G

2

pKa of COOH on amino acids

10

pKa of NH3+ on amino acids

10

lysine R group pKa at pH 7

6

histidine R group pKa at pH 7

12

arginine R group pKa at pH 7

4

aspartate R group pKa at pH 7

4

glutamate R group pKa at pH 7

Polar uncharged

serine, threonine, cysteine, asparagine, and glutamine are

Polar positive

lysine, histidine, arginine

Polar negative

aspartate and glutamate are

Aromatic

phenylalanine, tyrosine and tryptophan are

Non polar

valine, isoleucine, leucine, alanine, glycine, proline and methionine are

-20

delta G of hydration of tyrosine and tryptophan

About 0

delta G of hydration of phenylalanine

-20

one hydrogen bond group is about ____ delta G of hydration

Delta G of hydration

molar free energy change for transferring the molecule from vacuum to water

+10

delta G of hydration for alanine, valine, leucine, and isoleucine are about

About 0

delta G of hydration for methionine is about

Less

disulfide bond ability makes delta g of hydration

-20

delta G of hydration for serine and threonine is about

-40

delta G of hydration for asparagine and glutamine is about

-300 kj/mol

the values for the charged forms of lysine, arginine and histidine, aspartate and glutamate (delta G)