THYROID GLAND

THYROID GLAND

Butterfly shaped gland

Neck

Where is the thyroid gland located

CALCITONIN

Secreted by parafollicular C cells.

THYROID HORMONE

Secreted by thyroid follicular cell. Regulates body metabolism and neurologic development.

TSH

circulates to the thyroid gland and leads to increased production and release of thyroid hormone.

T3

Biologically active forms of thyroid hormone

THYROGLOBULIN

Prohormone. Tumor marker for thyroid cancer.

Graves disease

THYROID AUTOIMMUNE DISEASES: Hyperthyroidism

Hashimoto’s thyroiditis

Hypothyroidism:
o Chronic lymphocytic thyroiditis
o Thyroid peroxidase (TPO) antibodies

Amiodarone

Induced Thyroid Disease

THYROTOXICOSIS

Response of peripheral tissues to an excess of thyroid hormone

GRAVE’S DISEASE

The most common cause of thyrotoxicosis

PARATHYROID GLAND

Major function is to maintain the body's calcium level. They are the smallest (20-40 mg) endocrine gland and have a beanlike shape.

Ionized

Calcium that is unbound or free, 45% (around 50%). Physiologically active

Burnett’s syndrome

Milk-alkali syndrome. Ingestion of calcium with alkali (carbonate or barcarbonate)