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Vocabulary flashcards summarizing essential structures, proteins, ions, and physiological concepts involved in human muscle contraction and muscle types.
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Motor Unit
A motor neuron together with all the skeletal muscle fibers it innervates; the basic functional unit for producing muscle force.
Myofibril
Cylindrical bundle inside a muscle fiber composed of repeating sarcomeres that houses actin and myosin filaments.
Sarcomere
The repeating structural and contractile unit of a myofibril, bordered by Z-lines and containing thin and thick filaments.
Sarcoplasmic Reticulum
Specialized endoplasmic reticulum that surrounds myofibrils and stores/releases Ca2+ required for contraction.
Sarcoplasm
The cytoplasm of a muscle cell, containing organelles, glycogen, and myoglobin.
Sarcolemma
The plasma membrane of a muscle fiber capable of propagating action potentials; invaginated by T-tubules.
T-Tubule
Invagination of the sarcolemma that carries action potentials deep into the muscle fiber to trigger Ca2+ release.
Sliding Filament Model
Explanation of muscle contraction in which thin filaments slide past thick filaments, shortening the sarcomere in an all-or-nothing manner.
Troponin
Calcium-binding protein on thin filaments that moves tropomyosin to uncover myosin-binding sites on actin.
Tropomyosin
Rod-shaped protein that blocks myosin-binding sites on actin until shifted by Ca2+-bound troponin.
Myosin Head (Cross-bridge)
Globular part of the myosin molecule that binds actin, performs the power stroke, and hydrolyzes ATP.
Power Stroke
The pivoting motion of the myosin head that pulls actin toward the sarcomere center, generating contraction.
Neuromuscular Junction
Synapse where a motor neuron releases acetylcholine to stimulate a skeletal muscle fiber.
Acetylcholine (ACh)
Neurotransmitter released at the neuromuscular junction that depolarizes the sarcolemma.
Calcium Ion (Ca2+) in Contraction
Ion released from the sarcoplasmic reticulum that binds troponin, enabling cross-bridge formation.
ATP in Muscle Contraction
Energy molecule that detaches myosin from actin and re-cocks the myosin head after hydrolysis to ADP + Pi.
Rigor Mortis
Post-death condition where lack of ATP leaves myosin bound to actin, causing sustained muscle contraction.
Motor Unit Recruitment
Progressive activation of additional motor units to increase muscle force as stimulus intensity rises.
Submaximal Stimulus
A stimulus below maximal intensity that activates only some of the available motor units.
Maximum Stimulus
Highest stimulus intensity that recruits all motor units within a muscle.
Skeletal (Striated) Muscle
Voluntary muscle with striations and multiple peripheral nuclei that contracts via sarcomeres.
Cardiac Muscle
Striated, involuntary heart muscle with one or two central nuclei and interconnected by intercalated discs.
Intercalated Disc
Specialized junction between cardiac muscle cells containing gap junctions that synchronize contractions.
Smooth Muscle
Involuntary, non-striated muscle with a single central nucleus that contracts without sarcomeres and is controlled by the autonomic nervous system.
Muscular Pump
Action of skeletal muscle contractions squeezing blood and lymph vessels to aid circulation.
Thin Filament
Actin-based filament in a sarcomere that interacts with myosin during contraction.
Thick Filament
Myosin-based filament in a sarcomere responsible for force generation through cross-bridge cycling.
Autonomic Nervous System
Portion of the peripheral nervous system that regulates involuntary functions and controls smooth and cardiac muscles.
Mitochondrial Abundance (in Muscle Cells)
High density of mitochondria, especially in cardiac muscle, providing ATP for sustained contraction.