Tertiary Structure Stabilizing Forces

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7 Terms

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What are tertiary structures

  • Made by a combination of secondary structures

  • More ions range/ link distant aa

  • More complex features to create unique functions

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Types of Tertiary Structure Stabilizing Forces

  • Hydrophobic interactions

  • Hydrogen bonds

  • Electrostatic interactions

  • Water of Hydration

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Hydrophobic interactions

between hydrophobic side chains. Interactions make stable bonds. Non-covalent

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Hydrogen bonds

Non-covalent bonds

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Electrostatic interactions

between positive and negative side chains

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Water of hydration

Charges interact with water if in an aqueous solution

  • Water distributes charges and creates stable bonds

  • water is polar and can react with polar groups to increase their functionality

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Disulfide bond

insulin. Secondary and primary structure get bound to eachother. Only covalent link that contributes to the structure. Peptides just chain together