Common GPCR Signaling Pathways 2

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4 Terms

1
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What enzyme does Gq activate?

Phospholipase C (PLC).

2
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What does phospholipase C (PLC) do?

It breaks PIP2 into IP3 and DAG.

3
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What do IP3 and DAG do?

IP3 releases calcium from the endoplasmic reticulum, and DAG activates protein kinase C (PKC).

4
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What is the overall purpose of these pathways?

To amplify hormone signals and regulate many processes like metabolism, muscle contraction, and secretion.