medical moment

Ca of syphillis

Treponema pallidum

Epidemiology of syphillis

Human resorvoir only

Most in 1941-1946

West and south US

72% cases are Homosexual men 20-29 in 2011

3 stage of syphillis

Primary

Secondary

Late

Primary stage of syphilis

No symptoms for years

• Chancre = firm, round, small, and painless.

Secondary stage syphillis

Skin rash and mucous membrane lesions

• Not itchy

– fever, weight loss , fatigue

resolve with or without treatment.

Late stage syphilis

,

– damage the internal organs, including the brain,

nerves, eyes, heart, blood vessels, liver, bones, and

, gradual blindness, and dementia.

– may be serious enough to cause death.

Three physical stage syphilis

Chancre

Rash

Gumma

Congenital syphilisi

Miscarriage

Stillborn

Death

Deform

jaundice

Prevention syphilis

Long-term mutually monogamous relationship

• use of latex condoms

Syphilis: Treatment

:

single injection Benzathine penicillin G

• No immunity with recovery

Ca of candidiasis

Candida alibicans

candidiasis Is

Ubiquitous yeast

Opportunistic infection

Virulence factors candidiasis (pathogenisis)

Adherence molecule

Acid protease- easier to cling to spots

Hyphal form- increase tissue penetration

Epidemiology candidias

isimmunocompromised people

HIV - not in HASRY therapy (on track to aids )

Sign and symptom candidias

Fever

Mouth/tongue dysphasia

White patches

Infection of hair nail skin

Lesions

Treatment of candidias

Fluconazole

IV

Antifungal lozenges

early treatment of oropharyngeal to prevent spread

Ca of aids

HIV

Which is disease hiv or aids

AIDS

Which is virus hiv or aids

HIV

epidemiology of aids

Southern US

Black American

25-34 year old

Homosexual men

First cure of hiv

Woman had cancer and got stem cell transplant

What region has most hiv

Africa

HIV not transmitted by

Saliva tears sweat

HIV transmitted by

Semen / blood

Come contact with lesion on skin

Dried blood is 90% ineffective

Risk factor of hiv

Vaginalis delivery

High viral load

Lack of vitamin A

Ca of diptheria

Corynebacterium diptheriae

Sign and symptom diptheria

Sore throat

Oozing fluid from throat thickens to pseudomembrane

Airway obstruction

Diptheria complications

Air way blocked

Heart damage

Kidney failure

Pathogenesis diptheria

respiratory and physical contact

• Toxin produced causes hosts cells to

engulf bacterium and then blocks protein synthesis resulting in cell death

Epidemiology diptheria

.001 cases in us

Endemic in developing countries

Epidemic Soviet Union

Treatment diptheria

Antitoxin

Erythromycin and penicillin

Open airway surgically

Prevention of diptheria

Dtap or tdap vaccine

Diptheria outbreak

Sled dog in nome Alaska

Stopped outbreak

Ca meningitis

Haemophilus influenza

Info about mengitis

Fastidious non spore forming human are only natural host

Sign and symptom mengintis

Fever headache stiff neck cellulitis arthritis sepsis

Hearing loss

Meningitis transmission

Respiratory droplet

Pathogenesis mengitis

MO invade mucosa enter blood stream

Inflammation

Of immune system dosent stop, spread to joint pleura meninges lung

Epidemiology meningitis

Developing countries

Children younger than 2

Peak at 6-9 months

Meningitis treatment

antibiotic- fluoroquinolones, macrolides

Cephalosporin with b lacatmase

Meningitis prevention

Hib vaccine

Kid under 5

Given at 2 months