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why should we study cells
they are the foundation of biology
what system is the body organized into
cells→tissues→organs→ organ systems→ organisms
who discovered the cell and when
Robert hooke, 1665
who saw the living microorganism
anton van leeuwenhoek
who came up with cell theory
schleiden (plant), Schwann (animal), Virchow
what are the 3 parts of cell theory
all living things are made up of cells
the cell is the basic unit of life
cells come from pre existing cells
what are the 2 types of cells
prokaryotic and eukaryotic
what is a prokaryotic cell
no nucleus, no membrane bound organelles, small and simple (bacteria)
what is a eukaryotic cell
nucleus, organelles, larger and complex (plants, animals, fungi, protists)
common features of all cells
plasma/cell membrane (controls entry/exit)
cytoplasm (jelly like fluid inside)
DNA (genetic instructions)
ribosomes (protein builders)
light microscope
uses visible light, up to 1000x magnification
electron microscope
uses beams of electrons, much higher resolution
when and who discovered the cell
1665- Hooke, Leeuwenhoek
cells must remain ____
small
_______ to ______ ratio is critical
surface area, volume
a large surface area to volume ratio is an _________ exchange of nutrients/waste
efficient
if the cell is too big and inefficient
it cannot support itself
compartmentalization
separation of cellular functions into organelles, increases efficiency and specialization
nucleus structure
double membrane, pores, nucleolus
nucleus function
stores DNA, directs activity, makes ribosomes
function of nucleolus
synthesizes ribosome
function of pores
lets ribosomes out
function of double membrane
security
ribosomes are found in __________
both prokaryotes and eukaryotes
free ribosomes are
proteins for cell use
bound ribosomes (RER) are
proteins for secretion
ribosomes are the
universal feature of life
_____ have different machinery to synthesize ribosome
prokaryotes
rough ER
protein modification
smooth ER
lipid synthesis, detox
golgi apparatus/body
package/ships proteins (and lipid)
vesicles/vacuoles
transport and storage
lysosome
digestive enzymes
aproposis
program cell death
lysosomes are _____ bag of cell
suicidal (hydrolase enzyme)
hydrolytic
break down
lysosomes are present in many ____
numbers
if there are too many lysosomes it ______
self destructs and bursts, destroying what it comes into contact with
mitochondria is surrounded by
a double membrane
mitochondria is the _____ of the cell
powerhouse
mitochondria has its own _____
DNA and ribosomes (semiautonomous)
mitochondria’s energy source is ____
ATP
where is ATP stored in the mitochondria
cristae
where is chloroplasts located
in plants
what are the 2 reactions in chloroplasts
light and dark
where do light reactions take place
grana/thylakoid
where do dark reactions take place
stroma
what is the cytoskeleton composed of
microtubules, microfilaments, and intermediate filaments
what does cyto mean
cell
functions of cytoskeletonÂ
shape, transport, movement
cytoplasm
material within a living cell enclosed by the cell membrane
what is cytoplasm comprised of
cytosol, organelles, and various inclusions
cytoplasm’s function
act as the site for most cellular activities
3 parts of the cytoplasm
cytosol: gel like watery substanceÂ
organelles: specialized structures within the cell
inclusions: non-membranous structures serving as storage sites for nutrients and other substances
where are peroxisomes located
inside almost all eukaryotic cells
what are perixosiomesÂ
small membrane bound organelles that help keep the cell safe by breaking down certain harmful substancesÂ
what do peroxisomes break down
hydrogen peroxide
catalase
enzyme peroxisosomes use to convert water into oxygen
centrioles play an essential role in
cell division, organization, and the formation of cilia and flagella
centrioles are only present in
animal cells
shape of a centriole
cylindrical, microtubule arranged at right angles to form the centrosome
what are centrioles built from
9 sets of microtubule triplets arranged in a 9+0 pattern
cilia
hairlike extensions that stick out from the surface of eukaryotic cells
what is cilia and flagella made of
microtubules wrapped in a plasma membrane covering
main job of cilia
movement of the cell itself or materials, anchored by a basal body
arrangement of cilia
9+2, 9 pairs of microtubules in a ring, 2 in center
cell wall is only located in
plant cells
what is the cell wall
rigid structure that provides support, protection, and shape
cell wall is primarily composed of
cellulose, hemicellulose, and pectin
what is the vacuole
membrane bound organelles (tonoplast) that serve essential functions in storage, involvement in digestion/waste removal, and regulating cellular homeostasis
what vacuole do plans have
one big central
what vacuole do animals have
many small
contractile vacuole
osmoregulation regulates amount of water in body (unicellular)
what is the main difference between free and bound ribosomes
free synthesizes proteins within the cell, bound produces proteins for export or incorporation into cell membranes
what is the nucleolus primarily responsible for producing
rRNA and ribosomal subunits
what are cytoskeleton filaments that form spinal fibers to separate chromosomes in mitosis
microtubules
the endosymbiotic origin of mitochondria/chloroplasts evolved from
engulfed prokaryotic cells
what helps maintain cell turgor pressure in plant cells
the central vacuole
free floating ribosomes synthesize proteins that function in the
cytosol
what enabled bacterial cells to adhere to surfaces/exhange DNA
pili
tay Sachs disease is caused by the malfunction of
lysosome
most important for muscle contraction in the cytoskeleton are
actin microfilaments
where is chromatin foundÂ
the nucleus
the order of transport
Rough ER→ Golgi→ transport vesicle → plasma membrane
pancreatic cells secrete proteins needing
rough er and Golgi
phospholipid bilayer is made up of
hydrophilic heads and hydrophobic tails
proteins in the phospholipid bilayer
channels, carriers, receptors
cholesterol in the phospholipid bilayer
keeps membrane fluid
carbs in the phospholipid bilayer
acts as ID tags for cell recognition
what is passive transport
movement without ATP, from high to low concentration
types of passive transport
diffusion, osmosis, and facilitated diffusion
diffusion
molecules lose from high to low concentration, all types
osmosis
only water or solvent membrane move from high to low, selectively permeable membrane
2 types of osmosis
endosmosis: inflow of water (enter)
exosmosis: outward flow of water (exit)
facilitated diffusion
molecules use protein channel to move
tonicity
amount of dissolved substances (solute) in the solution
isotonic
amount of solute outside the cell= amount inside the cell
cell stays the same size because water moves in and out equally
hypotonic
solution outside cell has less solute and more water than inside the cell
cell gets bigger→ water moves into the cell
hypertonic
solution outside the cell has more solute and less water than inside the cell
gets smaller because water moves out of the cell
active transport
requires energy, moves from low to high