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Blood
A sticky, opaque fluid and the body's only fluid tissue, consisting of liquid plasma and formed elements
Homeostasis (Blood Function)
Maintenance activities including transport (gases, nutrients, waste products, regulatory/processed molecules), regulation of pH and osmosis, maintenance of body temperature, protection, and blood clotting.
Plasma
The liquid component of blood; a pale yellow fluid that is mostly water (91%) and contains proteins (7%)
Formed Elements
The cellular components of blood: Erythrocytes (RBCs), Leukocytes (WBCs), and Platelets
Hematocrit
The percentage of RBCs out of the total blood volume
Albumin
The most abundant plasma protein (58%), which helps maintain osmotic pressure
Fibrinogen
A plasma protein (4%) that is converted to fibrin during clot formation.
Leukocytes (WBCs)
Complete cells responsible for the body’s defense against infection and removing dead cells and debris by phagocytosis.
Polycythemia
An RBC count that is above the normal value
Anemia
A condition indicated by an RBC count below the normal value. Variations in the size and shape of RBCs can be a prediction of this.
Urine
A filtrate from blood that acts as a medium for the excretion of water, salts, acids, bases, and metabolic waste products (like urea, creatine, uric acid).
Urine Production
Produced by the processes of Filtration, Tubular reabsorption, and Tubular secretion
Urea
The principal end product of protein metabolism and comprises about half (½) of the total solids in urine
Creatinuria
A condition where an abnormal amount of creatine occurs in the urine; may occur during starvation, diabetes mellitus, prolonged fever, and pregnancy
Glycosuria
The presence of glucose in urine
Proteinuria/Albuminuria
The presence of protein in urine
Hematuria
The presence of blood in urine
Oliguria
A decrease in the flow of urine
Anuria
A total lack of urine excretion
Intracellular Fluid (ICF)
Fluid that is located inside cells
Extracellular Fluid (ECF)
Fluid located outside cells, which includes interstitial fluid and plasma.
8%
Blood accounts for approximately _____ of body weight, and the average volume for males is 5–6 L (1.5 gallons), and 4.5 L for females
7.35–7.45
. Blood is a sticky, opaque fluid, with a normal pH range of _______ and a temperature of 38°C
Globulins
(38% of plasma proteins) function in immunity (antibodies and complement), transport (e.g., binding to hormones), and as clotting factors
Erythrocytes (RBCs)
constitute about 95% of formed elements and carry hemoglobin to transport O₂ and CO₂.
infection
The normal total WBC count is 5,000–9,000 WBCs/mL. A count above this value indicates
Neutrophils
The most numerous type of WBC is _________ (60%-70%), followed by Lymphocytes (20%-25%).
Platelets (or thrombocytes)
are just cell fragments (without a nucleus) and are responsible for blood clotting. The normal count is 250,000–400,000/cubic mm blood
60
The kidneys filter the body’s entire plasma volume __ times each day
Uric acid
is a product of the metabolism of purines from nucleoproteins, and increased output is seen in patients with gouty arthritis.
Urine
______ is normally pale yellow or amber in color, and freshly voided urine has an aromatic odor
4.6–8
The normal pH range for urine is ____, with an average value of 6.3
Polyuria
is a greater amount of urine excretion than normal and is seen in conditions such as diabetic patients.
Blood Chemistry
The composition of materials dissolved or suspended in plasma (like Glucose, Urea, Nitrogen, Bilirubin, and Cholesterol) can be assessed through _________ _______ tests
5L
Total blood volume is approximately
neutrophil
Phagocytizes microorganisms and other substances
Basophil
raleases histamine, which promotes inflammation, and heparin, which prevent clot formation.
eosinophil
releases chemical that reduces inflammation, attacks certain worm parasites
lymphocyte
produces antibodies and other chemicals responsible for destroying microorganisms; contributes to allergic reaction, graft rejection, tumor control, and regulation of the immune system
monocyte
phagocytotic cell in the blood; leaves the blood and becomes a macrophage, which phagocytizes bacteria, dead cells, cell fragments, and other debris within tissues.
platelet
forms platelet plug, releases chemicals neccesarry for blood clotting
4.6-6.2; 4.2-5.4
Red blood cell count(million/meu L)–
Male _____ million/ m L
Female ______ million/ m L
14-18;12-16
measurement (grams of hemoglobin per/mL of blood)
–
Male ________ g/100mL
–
Female ______ g/100mL
40%-52%; 38%-48%
Hematocrit measurement
(percent volume of)
Male: _____
Female: ——-
5000-9000
White blood cell count ( m L)
Male and Female _________ WBCs/ m L
60%-70%
Differential white blood cell count (the percentage of each type of WBC)
Neutrophils:
20%-25%
Differential white blood cell count (the percentage of each type of WBC)
Lymphocytes
3%-8%
Differential white blood cell count (the percentage of each type of WBC)
Monocytes
2%-4%
Differential white blood cell count (the percentage of each type of WBC)
Eosinophils
0.5%-1%
Differential white blood cell count (the percentage of each type of WBC)
Basophils