The Big Five

The Big Five

Candida krusei

Candida tropicalis

Candida parapsilosis

Candida glabrata

Candida albicans

Candida krusei commonality

Least common

Candida krusei CHROM Agar

Rough pink with a white border

Candida krusei morphology

“Tree like” Ballistoconidia

Candida krusei Fluconazol

Constitutive/ natural fluconazol R

Candida tropicalis commonality

Most virulent

Candida tropicalis population

Leukemia

Candida tropicalis CHROM Agar

Deep blue

Candida parapsilosis Disease (2)

Endocarditis

Blood stream infection

Candida parapsilosis Morphology (2)

Single blastoconidia out of junction

Macaroni-shaped pseudohyphae

Candida glabrata Disease

UTI

Candida glabrata test (2)

Smaller on BA than on EMB!

Metabolize trehalose

Candida glabrata CHROM Agar

Mauve, waxy

Candida glabrata morpholohy 3)

No pseudohyphe

Tiney cells

Micky mouse ears when bud

Candida glabrata Fluconazole

Inducible fluconazole R

Candida albicans Commonality

Most common

Candida albicans Population (4)

Immunocompromised

Indwelling catheter

Broad-spectrum antibiotics

HIV Signal disease

Candida albicans Disease (4)

Thrush = HIV Signal Disease

Vaginitis (Yeast infection)

Candidemia (Bloodstream)

Esophagitis (AIDS)

Candida albicans Tests (2)

Grow on BA star-like projections

Germ tube test +

Candida albicans CHROM Agar

Teal

Candida albicans Morphology

Terminal chlamydoconidia

Candida albicans Reservior (1)(4)

Normal flora

GI tract

Skin

Oral cavity

Vaginal tract (Small #)