MEDICALLY IMPORTANT YEASTS

Spherical to elongate yeast-like cells or blastoconidia that reproduce by budding

candida

Candida spp.color pigmentation is usually

absent

A primary or secondary mycotic infection caused by

members of the genus Candida.

candidiasis

Candidiasis Involvement may be localized to the

mouth,throat skin, scalp, vagina

Commensal of mucous membrane and GI tract.

Candida albicans

Candida albicans Macroscopic morphology:

Creamy, smooth colonies appear rapidly at 25 C

Candida albicans Microscopic morphology:

Round to ellipsoidal cells

Candida albicans germ tube?

positive grows with cyclohexamide

Candida albicans on CHROMagar

light blue or green

Occasional cause of candidemia and mucosal infection

Candida dubliniensis

Candida dubliniensis resistant to

fluconozale

Candida dubliniensis Macroscopic morphology:

Creamy, yeast colonies appear rapidly at 25 C

Candida dubliniensis Microscopic morphology:

Round to ellipsoidal cells

Candida dubliniensis is germ tube pos or na

positive

Candida dubliniensis Grows on media with

cycloheximide

Candida dubliniensis color on chromagar

dark green

C. albicans # of chlamydospores

1-2

C. albicans Xylose Assimilation test result

positive

Sucrose Assimilation test result

variable

C. albicans 45 c test result

positve

C. dubliniensis # of chlamydospores

pairs, triplets and clusters

C. dubliniensis xylose assimilation test result

variable

C. dubliniensis sucrose assimilation test result

positve

C. dublinensis 45 c test result

negative

Major cause of septicemia and disseminated candidiasis.

candida tropicalis

candida tropicalis Macroscopic morphology:

Creamy-colored colonies form rapidly at 25 C

candida tropicalis germ tube neg or pos

negative

Candida tropicalis grows on what temp

40c

Candida tropicalis produces what color

blue

Candida krusei Also known as

Issatchenkia orientalis or Pichia kudriavzevii

Candida krusei resitant to

fluconizale

Candida krusei Macroscopic morphology:

Forms flat, dry, cream-colored colonies at 25 C

Candida krusei germ tube pos or neg

negative

Candida krusei growth on media containing cycloheximide

variable

Candida krusei temp that it grows on

37c

Candida krusei CHROMAgar color

pink

urinary tract and blood infections

Candida glabrata

Candida glabrata resistance to

amphotericin b and fluconazole

Candida glabrata Macroscopic morphology:

Forms small, white, cream-colored colonies at 25 C

Candida glabrata growth on media containing cycloheximide

Negative