Rabies

Lyssavirus

Rabies is caused by the ____

saliva

Rabies is transmitted through ____ contact with broken skin

zoonotic

rabies is ____, which means it spreads from animal reservoirs

CNS

rabies travels from the point of entry to the ____

muscle

stage 1 of rabies infects ____ cells, and is initially non specific

stage 1

what stage of rabies are the following symptoms from: fever, headache, nausea, abnormal sensation around the bite site (itching, burning, numbness)

CNS

stage 2 of rabies infects ____, causing patients to experience neurological symptoms

stage 2

what stage of rabies are the following symptoms from: anxiety, agitation, dysphagia (difficulty swallowing), paralysis, episodes of delirium, and hydrophobia

99.9

rabies has ____ % fatality if neurological symptoms develop

coma

a  ____ will precede death, which marks the final 3-7 days

stage 1

the virus is replicated in muscle cells surrounding the wound

axonal transport

the virus travels along peripheral nerves to CNS by ____. This journey may take weeks.

spinal cord motor neurons

the final destination of the Lyssavirus is the _____

stage 2

The virus replicates in CNS, causing neurological symptoms

salivary glands

In the final stages of rabies, the virus travels back to the peripheral nerves and enters the ____ for dissemination

Postexposure prophylaxis

preventative medical treatment given after exposure to a pathogen to prevent infection

first few

to be effective, immunization for rabies must be given within the ____ days of exposure

active immunization

4 doses of rabies vaccine

passive immunization

human rabies immunoglobulin