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NORMAL VOLUME OF URINE IN 24 HOURS
600-2000ML
AVERAGE URINE VOLUE
1200-1500ML
NIGHT TO DAY RATIO OF URINE VOLUME IS?
1:2 OR 1:3
WHAT IS THE REQUIRED VOLUME OF ROUTINE URINALYSIS?
10-15ML
THIS IS WHEN THERE IS AN INCREASED IN URINE VOLUME
POLYURIA
WHAT ARE THE POSSIBLE CAUSES WHEN YOU ARE EXPERIENCING POLYURIA?
INCREASED FLUID INTAKE, DIURETICS, DIABETES MELLITUS AND DIABETES INSIPIDUS
THIS IS A DEFICIENCY OF ANTI-DIURETIC HORMONE/ARGININE VASOPRESSIN OR UNREPONSIVENESS TO THE HORMONE (NEPHROGENIC)
DIABETES INSIPIDUS
THIS DISEASE CAN CAUSE A PERSON TO URINATE FOR UP TO 15 LITERS PER DAY
DIABETES INSIPIDUS
Which of the following is a symptom of Diabetes Insipidus?
A. Decreased urine output.
B. Increased thirst.
C. Low blood pressure.
D. Weight gain.
B
In Diabetes Insipidus, what is the underlying issue in the case of unresponsiveness to ADH?
A. Insufficient production of ADH.
B. Excessive production of ADH.
C. Damage to the collecting ducts and loop of Henle.
D. Overactive collecting ducts and loop of Henle.
C
DEFECTIVE RENAL SALT AND WATER ABSORPTION MAY BE DUE TO __
DIURETICS
DEFECTIVE RENAL SALT AND WATER ABSORPTION IS THE ABNORMALITY OF RENAL TUBULES RESULTING TO?
SODIUM WASTING AND IMPAIRMENT OF COUNTERCURRENT MECHANISM
THIS IS WHEN THE FUNCTIONING TISSUE IS DIMINISHED. THE ABILITY TO CONCENTRATE URINE IS GRADUALLY LOST
PROGRESSIVE CHRONIC RENAL FAILURE
DIABETIC MELLITUS WITH HYPERGLYCEMIA
OSMOTIC DIURESIS
THIS IS WHEN EXCESSIVE AMOUNTS OF GLUCOSE ARE EXCRETED, CAUSING A SOLUTE DIURESIS
OSMOTIC DIURESIS
THIS IS A DEFECT IN EITHER PANCREATIC PRODUCTION OF INSULIN OR FUNCTION OF INSULIN
DIABETES MELLITUS
THIS IS A HYPOGLYCEMIC AGENT AND A HORMONE THAT FACILITATES CELLULAR OPTIC OF GLUCOSE INTO THE CELL AND INTO THE TISSUE OF THE HUMAN BODY
INSULIN
IN DIABETES MELLITUS, ___ WOULD REMAIN EXTRACELLULARLY AND CANNOT BE UTILIZED BY THE CELLS AND TISSUES FOR ENERGY
GLUCOSE
THIS RESULTS OT HIGH PLASMA GLUCOSE BUT KIDNEYS DO NOT REABSORBS THE EXCESS GLUCOSE
DIABETES MELLITUS
URINE MAY APPEAR DILUTED BUT SPECIFIC GRAVITY IS HIGH
A. DIABETES MELLITUS
B. DIABETES INSIPIDUS
A
IN DIABETES MELLITUS, THERE MAY BE MANIFESTATION OF ___ IN THE URINE
GLUCOSE
What is the primary reason for the increased urine output (polyuria) in individuals with untreated diabetes mellitus?
A. Increased production of anti-diuretic hormone (ADH)
B. Decreased production of anti-diuretic hormone (ADH)
C. Excessive reabsorption of glucose by the kidneys
D. Excessive excretion of glucose by the kidneys
D
What is the primary role of insulin in the body?
A. To increase blood glucose levels
B. To decrease blood glucose levels
C. To increase blood pressure
D. To decrease blood pressure
B
Why does glucose appear in the urine of individuals with untreated diabetes mellitus?
A. Increased production of glucose by the kidneys
B. Decreased reabsorption of glucose by the kidneys
C. Increased filtration of glucose by the kidneys
D. Decreased filtration of glucose by the kidneys
B
What is the term for the condition of having glucose in the urine?
A. Glycosuria
B. Ketonuria
C. Proteinuria
D. Hematuria
A
URINE IS TRULY DILUTED AND SPECIFIC GRAVITY IS LOW
A. DIABETES MELLITUS
B. DIABETES INSIPIDUS
B
THIS IS WHEN WATER IS NOT REABSORBED FROM PLASMA FILTRATE
DIABETES INSIPIDUS
THIS DISEASE IS CAUSED BY THE DECREASE OF ADH FUNCTION OR PRODUCTION
DIABETES INSIPIDUS
THIS IS WHEN THERE IS A DECREASED URINE VOLUME
OLIGURIA
WHAT ARE THE POSSIBLE CAUSES WHEN A PATIENT IS EXPERIENCING OLIGURIA
DEHYDRATION, RENAL CALCULI OR TUMOR
DISORDERS THAT ARE MANIFESTING OUTSIDE THE KIDNEY OR BEFORE THE KIDNEY
PRE-RENAL DISEASE
PRE-RENAL DISEASE ARE CONDITIONS THAT CAUSES ___ BLOOD PRESSURE AND ___ BLOOD VOLUME
A. HIGH; HIGH
B. LOW; LOW
C. HIGH; LOW
D. LOW; HIGH
WRITE E IF THERE IS NO CORRECT ANSWER
B
LOSS OF INTRAVASCULAR VOLUME ATTRIBUTED TO BLEEDING, DEHYDRATION, PROLONGED DIARRHEA, VOMITING, EXCESSIVE SWEATING AND SEVERE BURNS
PRE-RENAL DISEASE
SHIFTING IN INTRAVASCULAR FLUIDS TO EXTRACELLULAR SPACES
THIRD SPACING
OTHER CONDITIONS ASSOCIATED WITH PRE-RENAL DISEASE ARE?
CONGESTIVE HEART FAILURE, SEPSIS, ANAPHYLAXIS, RENAL ARTERY EMBOLIC OCCLUSIONS
THESE ARE CONDITIONS THAT ARE AFFECTING THE PRODUCTION OF THE URINE AFTER IT LEAVES THE KIDNEY, GENERALLY MEANS OBSTRUCTION
POST RENAL DISEASE
THIS RESULTS FROM HIGH GRADE OR LONG STANDING OBSTRUCTION OF THE URINARY TRACT
BILATERAL HYDRONEPHROSIS
THIS IS WHEN ENLARGED PROSTATE GLAND IS COMPRESSING THE SPHINCTER THAT CONNECTS THE URETHRA AND THE BLADDER OF A MALE PATIENT
PROSTATIC HYPERPLASIA OR CARCINOMA
THIS MAY BE DUE TO STONES, CLOTS, OR SLOUGHED TISSUES WHICH CAUSES OLIGURIA
BILATERAL URETERAL OBSTRUCTION
THIS OBSCURES THE PASSAGEWAY OF THE URINE THROUGH THE URETHRA
BLADDER STONES
THIS FORMS IN THE HOLLOW STRUCTURES OF THE URETERS
RENAL STONES
STRICTURE OR VALVES THAT CAUSE OLIGURIA
URETHRAL OBSTRUCTION
INFLAMMATION OF THE NEPHRONS AND GLOMERULUS
ACUTE GLOMERULONEPHRITIS
THIS IS THE MOST COMMON CAUSE OF ACUTE GLOMERULONEPHRITIS
STREPTOCOCCAL ASSOCIATED ACUTE GLOMERULONEPHRITIS
THIS IS THE MOST COMMON CAUSE OF INTERSTITIAL NEPHRITIS
DRUG ALLERGY
THESE HAVE ANTI-INFLAMMATORY PROPERTIES, THAT IS WHY THEY WOULD RESPOND TO ALLERGIC REACTIONS INDUCED BY THE DRUG INTERACTION
EOSINOPHILS
THIS IS THE DEPLEETION OF OXYGEN SUPPLY ATTRIBUTED TO BLOCKAGE, DIMINISHED BLOOD SUPPLY THAT AFFECTS THE OXYGEN SUPPLY OF THE BLOOD TO THE KIDNEYS RESULTING TO AN?
ACUTE TUBULAR NECROSIS
THE MOST COMMON CAUSE OF ACUTE TUBULAR NECROSIS IS THE ____ WHICH IS ATTRIBUTED TO THE TO HEART FAILURE OR HYPOTENSION
RENAL ISCHEMIA
ACUTE TUBULAR NECROSIS IS ATTRIBUTED TO?
HEMOGLOBINURIA OR MYOGLOBINURIA
LIBERATION OF THE HEMOGLOBIN FROM THE ERYTHROCYTES, AND IT OCCURS INTRAVASCULARLY MEANING THAT THE HEMOLYSIS OF RBCS HAPPEN INSIDE THE BLOOD VESSEL
HEMOGLOBINURIA
THIS MAY POSE OXIDATIVE STRESS THAT CAN FURTHER DAMAGE THE INTEGRITY OF GLOMERULUS AND NEPHRONS
HEMOGLOBIN
THE HARMFUL EFFECTS OF HEMOGLOBIN CAN BE SUBDUED BY ACTION OF AN ACUTE PHASE REACTANT CALLED?
HAPTOGLOBIN
THIS CAN INCREASE THE RESPONSE TO SEVERITY OF AN INTRAVASCULAR HEMOLYSIS
HAPTOGLOBIN
HEME PORTION OF THE MUSCLE
MYOGLOBIN
THESE OFFERS MORE AGGRESIVE OXIDATIVE STRESS TO THE GLOMERULUS AND NEPHRONS OF THE KIDNEYS
MYOGLOBIN
THIS IS THE BENEFIT OF HEMOGLOBIN BECAUSE IT POSES LESS NEPHROTOXIC LESS THAN HAVING EXPOSED TO HARMFUL EFFECTS OF MYOGLOBIN
HAPTOGLOBIN
THIS BINDS FREE HEMOGLOBIN AND IS FURTHER RECYCLES TO RECREATE NEW ERYTHROCYTES
HAPTOGLOBIN
THIS HAS NO CARRIER PROTEIN, HENCE NOTHING TO PROTECT THE KIDNEYS FROM THE OXIDATIVE STRESS THAT THIS IMPACTS ON THE GLOMERULUS AND NEPHRONS
MYOGLOBIN
WHICH OFFERS A MORE NEPHROTOXIC DAMAGE?
A. HEMOGLOBIN
B. MYOGLOBIN
B
MERCURY, CADMIUM, CARBON TETRACHLORIDE, GLYCEROL AND SOME ANTIBIOTICS ARE KNOWN TO BE?
NEPHROTOXIC AGENTS
TRUE OR FALSE. IF RENAL FAILURE BECOMES CHRONIC, WE SHOULD EXPECT INCREASED URINARY OUTPUT AND EXPECT THE PRESENCE OF POLYURIA
FALSE
THIS IS THE PROGRESSIVE AND IRREVERSIBLE LOSS OF RENAL FUNCTION ATTRIBUTED TO SEVERAL DISEASES
CHRONIC RENAL FAILURE
THIS IS WHEN URINE SPECIFIC GRAVITY IS LOW AND PROTEINURIA, CASTS AND RENAL CELLS MAY BE EVIDENT
CHRONIC RENAL FAILURE
TUBULAR DYSFUNCTION WITH POLYURIA IN EARLY STAGE OF THE DISEASE AND LATER PROGRESSES INTO OLIGURIA OF CHRONIC RENAL FAILURE
PYELONEPHRITIS/INTERSTITIAL NEPHRITIS
THIS IS WHEN THERE IS A BACTERIAL INFECTION OF THE UPPER URINARY TRACT: GLOMERULUS, NEPHRONS, KIDNEYS THEMSELVES ARE EXPERIENCING BACTERIAL INFECTION
PYELONEPHRITIS
WHEN A PATIENT HAS PYELONEPHRITIS, THE EXPECTED MICROSCOPIC FINDINGS ARE?
WBC, WBC AND BACTERIAL CASTS
PREDOMINANT CELLS SEEN IN PYELONEPHRITIS AS THIS ARE INITIAL RESPONDERS AGAINST BACTERIAL INFECTIONS
NEUTROPHILS
THIS IS WHEN PYELONEPHRITIS BECOMES CHRONIC AND WE WOULD ONLY SEE WBC AND WBC CASTS AND NOT BACTERIAL CELLS AS INFLAMMATION IS INDUCED BY A DRUG ALLERGY AND NOT BY AN INFECTIOUS BACTERIOLOGIC AGENT
INTERSTITIAL NEPHRITIS
HOW DO WE DIFFERENTIATE WBC FROM PYELONEPHRITIS FROM WBC FROM INTERSTITIAL NEPHRITIS?
DIFFERENTIAL STAINS LIKE STERNHEIMER-MALBIN AND HANSEL STAIN
THIS DEMONSTRATES THE PRESENCE NEUTROPHILS (PYELONEPHRITIS)
STERNHEIMER-MALBIN
THIS DEMONSTRATES THE PRESENCE OF EOSINOPHILS (FOR INTERSTITIAL NEPHRITIS)
HANSEL STAIN
THIS IS THE COMPLETE CESSATION OF URINE FLOW
ANURIA
CAUSES OF ANURIA ARE?
COMPLETE OBSTRUCTION, TOXIC AGENTS AND DECREASED RENAL BLOOD FLOW
THIS IS THE EXCRETION OF MORE THAN 500ML OF URINE VOLUME AT NIGHT AND THE SPECIFIC GRAVITY OF URINE IS LESS THAN 1.018
NOCTURIA
WHAT IS/ARE THE CAUSES OF NOCTURIA
PREGNANCY
THIS IS A ROUGH INDICATOR OF HYDRATION STATUS
URINE COLOR
URINE COLOR SHOULD CORRELATE WITH THE?
URINE SPECIFIC GRAVITY
NORMAL COLOR OF A URINE IS?
COLORLESS TO DEEP YELLOW
ABNORMAL URINE COLOR IS?
RED OR RED BROWN
URINARY PIGMENT THAT GIVES OFF THE YELLOW COLOR OF A URINE
UROCHROME
THIS IS THE MAJOR PIGMENT OF URINE
UROCHROME
THE PRODUCTION OF THIS URINARY PIGMENT IS DIRECTLY PROPORTIONAL TO METABOLIC RATE
UROCHROME
UROCHROME CAUSES AN INCREASE IN?
STARVATION, THYROTOXICOSIS, FEVER
URINARY PIGMENT THAT GIVES OFF THE PINK COLOR OF A URINE
UROERYTHRIN
THIS URINARY SEDIMENT MAY DEPOSIT IN AMORPHOUS URATES AND URIC ACID CRYSTALS
UROERYTHRIN
URINARY PIGMENT THAT GIVES OFF THE DARK YELLOW/ORANGE COLOR OF A URINE
UROBILIN
THIS IMPARTS THAT COLOR TO A URINE THAT’S NOT FRESH (INDICATOR)
UROBILIN
IF THE URINE IS NOT FRESH, BACTERIA WILL CONVERT UROBILINOGEN INTO?
UROBILIN
IF THE COLOR OF THE URINE IS COLORLESS/STRAW, THIS MAY INDICATE?
RECENT FLUID INTAKE
IF THE COLOR OF THE URINE IS PALE YELLOW, THIS MAY INDICATE?
POLYURIA, DILUTED RANDOM SPECIMEN
IF THE COLOR OF THE URINE IS DARK YELLOW, THIS MAY INDICATE?
CONCENTRATED URINE, STRENUOUS EXERCISE, FIRST MORNING URINE
IF THE COLOR OF THE URINE IS AMBER, THIS MAY INDICATE?
DEHYDRATION, FEVER, BURNS
IF THE COLOR OF THE URINE IS YELLOW GREEN TO YELLOW BROWN, THIS MAY INDICATE?
BILIRUBIN OXIDIZED INTO BILIVERDIN
IF THE COLOR OF THE URINE IS GREEN, THIS MAY INDICATE?
PSEUDOMONAS INFECTION
POSSIBLE COLOR OF THE URINE WHEN THERE IS INDICAN, AMITRIPTYLINE, METHOCARBANOL, CLORETS, METHYLENE BLUE AND CHLOROPHYLL
BLUE GREEN
PRESENCE OF INTACT RBC IN THE URINE PRESENTS WHAT COLOR/CLARITY
CLOUDY/SMOKY
DEMONSTRATION OF INTACT RBCS IN A GIVEN URINE SAMPLE
HEMATURIA
PRESENCE OF INTACT RBC IN THE URINE IS AN INDICATOR THAT A PATIENT MAY HAVE?
UPPER/LOWER URINARY TRACT BLEEDING
PRESENCE OF HEMOGLOBIN IN THE URINE PRESENTS WHAT COLOR/CLARITY
CLEAR/RED
LYSIS OF ERYTHROCYTES INSIDE THE BLOOD VESSEL
INTRAVASCULAR HEMOLYSIS