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The junctional folds of the neuromuscular junction are the site of ______ receptors?
Acetylcholine
The protein found in muscle cells that stores and releases oxygen needed is called?
myoglobin
When stimulated , muiscles cells will respond with _____ changes across the plasma membrane.
Electrical
Aerobic respiration produces _____ ATP than glycolysis.
more
what is found in thin filiaments?
1. Tropomyosin
2. F actin
3. troponin
How do smooth muscle myocytes differ from cardiocytes?
Smooth muscle myocytes have no T tubules while cardiac muscles do.
The characteristic that allows muscles to pull on bones and organs to create movement is called?
Contractility
What are two contractile proteins found in a myofibil?
1. Actin
2. Myosin
Which describe smooth muscle tissue?
1. uninucleate
2. mom - striated
The process of muscle excitation is a series of events that permit an impulse from a nerve to generate a polarization change called ------ potential in a muscle fiber.
Action Potential
The volatage meassured across the muscle cell at rest is about -90 M V Action Potential and is called the resting membrane.
potential
In what type of contraction does the internal tension build until it overcomes resistance and the muscle moves the load?
Isotonic
the steps of muscle relaxation in order.
1. The nerve signal ceases
2. AChE breaks ACh down
3. Active transport pumps in the sarcoplasmic reticulum begin to pump calcium back into the cisternae
4. Calcium releases from troponin
5. Tropomyosin covers the myosin binding sites.
Walls of the heart consist of ____ muscle tissue.
cardiac
The partial contraction of a resting muscle is known as which of the following?
muscle tone
The energy needed for short bursts of intense activity is provided by what?
1. Creatine Phosphate
2. ATP
what does excitation involce?
The generation of action potentials, and occur in both neurons and muscle fibers.
The progressive weakness and loss of contractibility that results from prolonged use of the muscles is known as muscle ?
fatigue
what are characteristics of cardiac muscle?
1. It has large stores of glycogen
2. it uses aerobic respiration almost exclusively
3. it is rich in myoglobin
what is the role of acetylchoinesterase?
It breaks down ACh, ending muscle stimulation.
What type of contraction maintians joint stability and posture.
isometric contraction
The portion of a myofibril from one Z disc to the next is called?
sarcomere
What are two regulatory proteins found in a myofibril?
1. troponin
2. tropomyosin
which proteins makes up the thick filaments of a myofibril.
myosin
The prevailing theory regarding muscle contraction is called ___ ____ theory?
Sliding filament theory
Which describes cardiac muscle tissue?
1. Striated
2. usually uninucleate
3. branching
All of the muscle fibers innervated by a single nerve fiber constitute a _______?
motor unit
When muscles stretch and recoil, they recoil to a shorted length. what is the property called?
elasticity
A synapse is the point where a nerve fiber meets a target cell. When the target cell is a muscle fiber, this type of synapse is called a _______ junction.
Neuromuscular junction
Which of the following occur during the relaxation phase of muscle contraction?
1. Calcium levels in the sarcoplasm fall
2. muscle tension declines
3. myosin releases the thin filaments
skeletal muscle exhibits alternating light and dark bands called?
Striations
How does muscle contraction occur?
the overlapping of myofilaments increases.
what is muscle tone?
The partial contraction of resting muscles.
What are the functions of smooth muscle ?
1. To constrict or dilate blood vessels to control pressure.
2. To move material through the digestive tract.
3. To regulate pupil diameter.
Which types of muscle tissue are considered involuntary?
1. cardiac
2. smooth
The neurotransmitter used in a neuromuscular junction is?
Acetylcholine
When a muscle is at rest, what molecule blocks the active sites on the actin molecules?
tropomyosin
Which are the characteristics of cardiac muscle cells?
1. they are resistant to fatigue
2. they contract nearly in unison
3. they contract with regular rhythm
within skeletal muscle cells , what extends from one Z disc to the next and constitutes one contractile until?
1. sarcomere
The voltage measured across the muscle cell at rest is about -90mv and is called the resting membrane?
resting membrane potential
Which describe smooth muscle?
1. smooth muscle has little SR
2. Smooth muscle has no T- tubules
3. smooth muscle is uninucleate
The type muscle contraction in which there is a change in length , but no change in tension is called ______ contraction.
Isotonic contraction
calcium is stored within the _____ ______ of a skeletal muscle cell.
sarcoplasmic reticulum
heart rate and contraction strength are controlled by ?
autonomic nervous system
Which affect twitch strength ?
1. Temperature of the muscle
2. How stretched the muscle was just before it was stimulated
3. Muscle fatigue
4. Stimulation frequency
actions that require physical strength typically involve ?
large motor units
a record of the timing and strength of a muscles contraction is called?
myogram
in the heart, what triggers the wave of electrical excitation that causes the heart to contract?
pacemaker
which are chacteristics of cardiac muscle?
1. it has large stores of glycogen
2. it is rich in myoglobin
3. it uses aerobic respiration almost exclusively.
what is the immediate trigger for the contraction of smooth muscle.
calcium ions
the minimum voltage necessary to generate an action potential ?
The threshold
what is the H band of a sarcomere?
a region within the A band that lacks thin filaments
Tonic contraction of ____ muscle plays an important role in maintain blood pressure and in keeping the intestine partially contracted.
smooth
what is the perimysium of a muscle?
the connective tissue layer covering individual bundles of muscle fibers.
Which three situations lead to fatigue in long duration exercise?
1. electrolyte loss
2. fual depletion
3. central fatigue
a muscle fiber shortens and generates force during the ____ period of a muscle twitch.
Contraction
fibers that are well adopted to aerobic respiration are called _____ twitch fibers?
Slow
where is single unit smooth muscle found ?
1. wall of stomach
2. wall of bladder
3. wall of uterus
Action potentials spread across the sarcolemma and continue down which structures into the sarcoplasm?
t tubules
which type of muscles contract more strongly?
warm
Muscle tissue is typically slow to contract and slow to relax?
smooth
discs are the thickened notched ends of the cardiac muscle cells which contain gap junctions.
intercalated
temporal summation to a state of fluttering contraction known as what?
incomplete tetanus
During repolarization ____ ions diffuse out of the cell, changing the membrane potential back to negative value.
potassium
what occurs when calcium binds to troponin?
The troponin tropmyosin complex changes shape and exposes the myosin binding sites (active site)
muscle tissue is typically slow to contract and slow to relax
smooth
what is the function of T tubules
to stimulate the terminal cisternae to release calcium
muscle cells contain _____ a starch like carbohydrate that provides energy during intense exercise.
Glycogen
at the synaptic knob of the motor neuron, calcium stimulates exoctosis of the synaptic vesicles to release the neurotransmitter ____ into the synapse.
Acetylcholine
The glycogen lactic acid system utilizes what molecules as fuel to generate ATP?
glucose
what causes skeletal muscle cells to be striated?
the alternating light and dark regions of the sarcomeres
what results in a weak contraction?
1. an over stretched muscle
2. an over contracted
once threshold has been reached a muscle fiber will contract fully, is know as what law.
all or none
during contraction the cooked myosin head binds to an exposed active site on the actin protein of the filament to form a cross bridge.
Actin
twitch strength varies with how stretched the muscle was just before the current stimulus.
true
the cross bridge created by the binding of a myosin head to an active site on an actin filament is broken by binding
ATP
which two types of muscle tissue can be autorhythmic?
1. smooth
2. cardiac
which process produces the most ATP?
aerobic respiration
contracting muscles against a load that resists movement is called?
Resistance
fatigue resistance is improved by _____ exercise which enhances the delivery and use of oxygen.
aerobic
each muscle fiber innervated by which of the following?
one motor neuron
where does the end plate potential occur?
motor end plate
actin and myosin serve what functions?
1. internal transport
2. chromosome movement
3.cellular movement
in muscle what does the source of ATP depend upon?
duration of exercise
on a myogram the stimulus and the twitch is known as the ______ period.
Latent
what is true the light bands in skeletal muscle.
they are called I bands in skeletal muscle.
the portion of a myofibril from one z disc to the next is called?
Sarcomere
infolding of the sarcolemma called transverse tubules are associated with two terminal cisternae. forming a unit called a?
Triad
the build up of lactic acid in the sarcoplasm has very little effect on twitch strength
true
the innermost layer of connective tissue that surrounds each muscle fiber is called?
Endomysium
complete (fused) _____ is the continuous forceful contraction in a muscle with no relaxation between stimuli
Tetanus
what happens when calcium ions bind to troponin?
tropomyosin moves off the active site on actin
the synaptic knob does not touch the muscle fiber but is separated by which structure?
synaptic cleft
which is not naturally seen in the muscles of the body?
complete tetanus
in an NMJ after acetylcholins diffuses across the synaptic cleft where does it bind to ligand gated channels
on the sarcolemma
the quick up and down voltage shift from negative to positive created by the movement of NA+ and K + across the cell membrane
action potential
what are smaller motor units used for?
fine motor control
cadiac muscle cells are considered ____ because they contract rhythmically and independently.
autorhythmic
what do neurons ans muscle cells have in common?
their membrane undergo voltage changes when stimulated.
As the myosin head releases the thin ilament muscle tesion declines during what is reffered to as the _____ phase of a muscle twich.
relaxation