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What form does subcutenanous abscesses take
Single or dissemineated purulnent subcut
What disease causes abscess on internal organs
Subcutaneous abscesses
Subcutaneous abscesses is a commensal of what tracts
Skin, respiratory, urogential & GIT
Predisposing factors of Subcutaneous abscesses
Mechanical trauma - umbilical cord, castration, rough surface
Immun disorders - PRRS & PCV2 (immunosupression diseases)
What disease does Trueperella pyogenes cause
Subcutaneous abscesses
etiological agent of Subcutaneous abscesses
Tureperella pyogenes
What is the major virulence marker of Trueperella pyogenes
Toxin - pyolizine
What action does the toxin of Subcutaneous abscesses have
Pyolizine - cytolytic, hemolytic, dermonecrotic
Source & route of infection of Subcutaneous abscesses
Infected pigs & environment
Damage skin
Name skin disease that can survive intracellular in macrophages
Swine pox, greasy pig & Subcutaneous abscesses
How does bacterimia occur in Subcutaneous abscesses
I occurs as the pus cannot escape the thick capsule on abscesses so it enters the lymph causes metastatic abscesses
pathogenesis of Subcutaneous abscesses
Adheres to the cell, penetrates macrophages
Has Ca++ dependent proteolytic activity - damages the immune system
Causes subcutaneous, intramuscular & internal abscesses
Where an abscesses be found in Subcutaneous abscesses
Subcutenous, intramuscular, internal organs
Abscess in subcut, intramuscular & on internal organs indicate what?
Subcutaneous abscesses
What age does Subcutaneous abscesses effect
Sows & fattening pigs
name a primary bacterial disease that effects sows & fatteners
Subcutaneous abscesses
In sows there is inflammation & degeneration of the mammary glands, what disease does it have
Subcutaneous abscesses
Name clincial signs of Subcutaneous abscesses
Sows - inflammation & degneration of mammary gland
Subcut, intramuscular & internal organ abcesses
Abcesses with thick fibrous capsules & greyscale pus
Disease of limbs - hot painful, swelling of coronary band
Itch & hairless
necropsy shows abcesses in different locations & enlarged lymph nodes what disease is this
Subcutaneous abscesses
What material is used for diagnosis of Subcutaneous abscesses
Abcesses swab, wound, mucus, joint fluid, milked, blood internal organs
What are the method of diagnosis of Subcutaneous abscesses
Bacteriology & PCR
Treatment of Subcutaneous abscesses
Chloramphenicol, thiamphenicol, florenphenicol, benyzlpenicliin, ampicillin
What is the treatment for large abcesses of Subcutaneous abscesses
Surgery - but dont Carry out in pig house
What type of vaccination is used for chronic Subcutaneous abscesses
Autovaccine
Itching, hair loss, with sore hot limbs, & greyscale pussy abcesses is a sign of what
Subcutaneous abscesses
What disease pathogenesis include ca++ dependent proteolytic action on immune system
Subcutaneous abscesses
PPRS & PVCS is a predisposing factor of what skin disease
Subcutaneous abscesses
PCV2 is a predisposing factor of what skin diseases
Subcutaneous abscesses & greasy pig
Umbilical cord & castration can lead to what type of infections
Streptococcus suis, staphylocccus hyicus, Trueperella pyogenes
Is Subcutaneous abscesses uqibitous
No
Chloramphenicol & thiaemphenical is useful for what skin disease
Subcutaneous abscesses
What is etiological agent of malignant edema
Clostridium septicum
What ages does it effect
All ages - fall of fatteners & sows
Name skin diseases that effect fatteners & sows
Malignant edema & Subcutaneous abscesses
What is the main virulence of malignant edema
Production of exotoxins poisoning & severe edema on neck
what type of toxin is responsible for malignant edema & what acivity does it have
Exotoxin - necrotic, enzymatic, haemolytic activities
Exotoxin poisoning occurs with what disease & bacteria
Malignant edema - clostridium septicum
Pathogenesis of malignant edema
States at site of infection anaerobic condition - produce toxins
Multiplies & intensifies - toxins may enter the blood stream & cause secondary foci on other tissues & organs
There is painful swelling cracking edema & reddish blue darkening of skin what is it?
Malignant edema
What is characteristic to malignant edema at the side of infection
Strong holding bristle on swelling
strong holding bristles on swelling is characteristics of
Malignant edema
What is characteristic of necropsy of malignant edema
Flatulence, edema in subcut of mandibular, muscle & serous membrane
Swollen muscle black dry swelling amber fluid
Spongy gas bubble in organs
Diagnosis of malignant s edema
Necropsy & lab exam
Control methods of malignant edema
Protect wounds, remove dead animals & clean pens
Is there specific prophylaxis of malignant edema
No
What is the treatment of malignant edema
There is none effective - only when implemented early
What skin disease requires sanitary slaughter
Malignant edema
Diseases has edema of mandible, swollen dry smelly black muscles & amber fluid
Malignant edema
Amber fluid is characteristic of
Malignant edema
What does PNES stand for
Porcine necrotic ear syndrome
What age does PNES effect
All ages
Name a chronic skin infection
PNES
What form does PNES normally take
chronic
What is the etiolgical agent of PNES
Mycoplasma haemosuis
Methods of transmission of PNES
Horizontal - direct & indirect
Vertical - pregnant sows
What are predisposing factors to PNES
Nutritional def - lysine, vit D and E
Excess phytase - reduces zinc absorption
Bed environmental conditions
Immunosuppressive agent - PVC2, PRRS, mycotoxin
Deficiency of vitmaine D & E can cause what skin disease
PNES
Excess pytase runs the risk of what?
PNES
PVC2 & PRRS are predisposing factors of what skin disease
Subcutenous abcesses & PNES
What is the pathogenesis of PNES
Where to membrane of RBC causing them to be deformed
They are recognized as abnormal by the spleen & removed from circulation
Loss in RBC cause anemia & bilirubinemia = jaundice
Autoimmune reaction to RBC = immune compromised
Clogs peripheral arteries of ears & tail = local necorsis
Subsequent infection of strep & staph
Which disease has the following symptoms Anemia, jaundice & splenomegaly
PNES - mycoplasma heamosuis (not leptospirosis)
Clinical signs of PNES
Anemia, jaundice, splenomegaly, cyanosis of ear
What is characteristic of necropsy in PNES
Anemia - planes, jaundice, spleen enlargement & watery blood
Watery blood can be seen in
PNES
Diagnosis methods of PNES
Clincial symptoms
Lab - blood smear, PCR, serolgoy
What bacteria is detected by blood smear
Mycoplasma haemosuis - PNES
Control of PNES
General - stimulate herd resistance, proper nutrient & magament
Specific - none but anti-circovirus works well
What is the specific prophylaxis of PNES
NONE - but anti-circovirus works well
Treatment of PNES
Oxytetrcycline & iron injection