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Alleles
Different forms of the same gene
Dominant
An allele that is always expressed (G)
Recessive
An allele that is masked when a dominant allele is present (g). Only expresses itself when homozygous recessive
Genotype
the letter combination or genetic makeup of an organism
Phenotype
physical characteristics of an organism
Homozygous
An organism that has two identical alleles for a trait (GG or gg)
Heterozygous
An organism that has two different alleles for a trait (Gg)
Probability
likelihood that a particular event will occur
Punnett Square
a tool used to predict the possible outcomes of a genetic cross
Monohybrid cross
A cross between individuals that involves one pair of contrasting traits (GG x gg)
Dihybrid cross
A cross between two individuals, concentrating on two definable traits (GGrr x ggRr)
Law of Independent Assortment
the law that states that genes separate independently of one another in meiosis
What is the phenotypic ratio of the F2 generation?
3:1
What is the genotypic ratio of the F2 generation?
1:2:1
Pedigree
A chart or "family tree" that tracks which members of a family have a particular trait
Incomplete dominance
When one allele is not completely dominant over another, the heterozygote has a phenotype between the homozygotes.
Complete dominance
The situation in which the phenotypes of the heterozygote and dominant homozygote are indistinguishable.
Codominance
A condition in which both alleles for a gene are fully expressed (mixture expression)
Multiple Alleles
three or more alleles of the same gene (blood type)
Sex chromosomes
Chromosomes that determine the sex of an individual (X and Y). XX = female and XY = male
Sex-linked inheritance
Inheritance of a genetic trait located on the sex chromosomes
Polygenic inheritance
occurs when multiple genes determine the phenotype of a trait (skin color)
Random fertilization
source of genetic variation caused by the unlimited number of possible sperm & egg combinations
True-breeding
Organisms that, when reproducing, create offspring of all the same variety.
Locus
Location of a gene on a chromosome
Test cross
the crossing of an individual of unknown genotype with a homozygous recessive individual to determine the unknown genotype
F1 generation (Mendel)
PP x pp
F2 generation (Mendel)
Pp x Pp
FOIL
First, Outer, Inner, Last
What is the phenotypic ratio of a dihybrid cross?
9:3:3:1
Pleiotrophy
A single gene that affects more than one trait
Epistatsis
a gene at one locus alters the phenotypic expression of a gene at a second locus
Dominant trait (pedigree)
is present and can disappear
Recessive trait (pedigree)
hides and can appear suddenly
X-linked recessive
carried by females and affects males
Mode of inheritance
the pattern in which a genetic disease is inherited through generations