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Unique characteristics of cardiac muscle
Involuntary, striated, branched cells with one nucleus; intercalated discs allow electrical connection; contracts rhythmically without fatigue
Systemic circulation
Delivers oxygenated blood to body cells and carries away waste
Pulmonary circulation
Carries blood to lungs to remove carbon dioxide and pick up oxygen
Heart chambers
2 atria receive blood; 2 ventricles pump blood out
Septum
Wall separating right and left sides of the heart
Heart valves
Ensure one-way flow of blood
Tricuspid valve
Right atrioventricular valve between right atrium and right ventricle
Mitral (bicuspid) valve
Left atrioventricular valve between left atrium and left ventricle
Pulmonary semilunar valve
Between right ventricle and pulmonary artery
Aortic semilunar valve
Between left ventricle and aorta
Erythrocytes
Red blood cells that transport oxygen
Leukocytes
White blood cells that fight infection
Thrombocytes
Platelets that help blood clot
Hematocrit
Percentage of red blood cells in blood volume (36–53%)
Purpose of hematocrit
Measures RBC levels to help diagnose anemia, dehydration, and other conditions
Neutrophils
Fight bacterial infections and inflammation
Eosinophils
Fight parasitic infections and trigger allergic responses
Basophils
Release histamine during allergic reactions
Monocytes
Clean up dead cells; become macrophages or dendritic cells
Lymphocytes
Defend against infections; B cells make antibodies, T cells destroy infected cells
Leukocyte percentages
Used by doctors to identify infections, allergies, and immune disorders
Plasma
Liquid portion of blood (92% water) that transports nutrients, gases, and maintains balance
Plasma proteins
Albumin (blood pressure), globulins (antibodies), fibrinogen (clotting)
Pathway of oxygenated blood
Lungs → pulmonary veins → left atrium → left ventricle → aorta → body
Pathway of deoxygenated blood
Body → vena cava → right atrium → right ventricle → pulmonary arteries → lungs
Blood types
A, B, AB, O with positive or negative Rh factor
Rh factor
Presence (+) or absence (-) of Rh antigen
Genotypes of blood types
A = AA or AO; B = BB or BO; AB = AB; O = OO
Type A blood
A antigens and anti-B antibodies
Type B blood
B antigens and anti-A antibodies
Type AB blood
A and B antigens and no antibodies
Type O blood
No antigens and both anti-A and anti-B antibodies
Punnett squares
Used to predict offspring blood types from parent genotypes
Cooley’s anemia
Genetic disorder (thalassemia) causing reduced hemoglobin production
Sickle cell anemia
Genetic disorder where red blood cells become sickle-shaped and block blood flow
Pericardium
Protective sac around the heart with fluid to reduce friction
Layers of heart wall
Epicardium (outer), myocardium (muscle), endocardium (inner lining)
Coronary arteries
Supply blood to the heart muscle
Splenomegaly
Enlarged spleen that filters blood and recycles iron