Organic Chemistry 331 Unit 3 SN vs E reactions

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28 Terms

1

Methyl + Big Alkoxide

SN2

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2

Methyl + Small Alkoxide

SN2

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3

Methyl + Strong Nucleophile

SN2

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4

Methyl + Protic Solvent

SN2

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5

Methyl + Aprotic solvent

SN2

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6

Methyl + strong base

SN2

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7

Methyl + bulky base

SN2

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8

Primary + big alkoxide

E2

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9

Primary + small alkoxide

SN2

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10

Primary + strong nucleophile

SN2

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11

Primary + protic solvent

SN2

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12

Primary + aprotic solvent

SN2

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13

Primary + strong base

SN2/E2

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14

Primary + bulky base

E2

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15

Secondary + big alkoxide

E2

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16

Secondary + small alkoxide

E2

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17

Secondary + strong nucleophile

SN2

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18

Secondary + protic solvent

SN1 (rearrange), E1 (if heat)

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19

Secondary + aprotic solvent

SN2

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20

Secondary + Strong base

E2/SN2

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21

Secondary + bulky base

E2

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22

Tertiary + big alkoxide

E2

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23

Tertiary + small alkoxide

E2

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24

Tertiary + strong nucleophile

SN1

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25

Tertiary + protic solvent

SN1 (rearrange), E1 (if heat)

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26

Tertiary + aprotic solvent

SN1/E1

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27

Tertiary + strong base

E2

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28

Tertiary + bulky base

E2

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