Blood Coagulation System & Protease Inhibitors

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4 Terms

1
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What is the role of the blood coagulation system?

It minimizes blood loss, hinders pathogen entry into circulation, and enhances the innate immune response through platelet activity.

2
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How does bradykinin contribute to immune defense?

causes vasodilation and attracts innate immune cells to sites of infection.

3
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What do protease inhibitors do?

They prevent tissue breakdown and invasion by pathogens, with 10% of plasma proteins acting as protease inhibitors.

4
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How does α2 macroglobulin function?

It traps proteases by undergoing a shape change to enclose the protease and prevent further interaction with substrates.