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What is the role of the blood coagulation system?
It minimizes blood loss, hinders pathogen entry into circulation, and enhances the innate immune response through platelet activity.
How does bradykinin contribute to immune defense?
causes vasodilation and attracts innate immune cells to sites of infection.
What do protease inhibitors do?
They prevent tissue breakdown and invasion by pathogens, with 10% of plasma proteins acting as protease inhibitors.
How does α2 macroglobulin function?
It traps proteases by undergoing a shape change to enclose the protease and prevent further interaction with substrates.