Polyethylene glycol_Medcard

Pharmacological Class

Osmotic laxative

Generic Name

polyethylene glycol)

Indications

A patient may receive polyethylene glycol/electrolyte for:

• Bowel cleansing prior to GI procedures (e.g., colonoscopy)

• Unlabeled: Acute iron overdose (whole bowel irrigation, pediatrics)

Mechanism of Action

• Acts osmotically to pull water into the intestinal lumen, causing:

  • Rapid diarrhea

  • Complete evacuation of bowel contents

• Electrolytes are included to prevent fluid and electrolyte imbalance

Assessment – 3 Priority Data (Before Giving)

1. GI status (abdominal pain, obstruction, perforation)
   → contraindicated if present

2. Fluid & electrolyte status (hydration, labs if indicated)
   → risk of dehydration, hypo-/hyper-electrolyte states

3. Cardiac/neurologic history (arrhythmias, seizures)
   → risk of arrhythmias or seizures

Adverse Reactions / Side Effects

MOST SERIOUS (Recognize Immediately)

1. Arrhythmias – palpitations, abnormal rhythm

2. Seizures – especially in patients with electrolyte imbalance

3. Severe dehydration/electrolyte imbalance – dizziness, weakness, syncope

MOST COMMON

1. Diarrhea (expected effect)

2. Abdominal bloating or cramping

3. Nausea or vomiting

Patient Education – 3 Priority Teaching Points

1. Expect frequent watery stools; bowel cleansing usually starts within 1 hour

2. Drink exactly as directed (large, rapid volumes are more effective than sipping)

3. Clear liquids only; avoid solid food, milk, alcohol, and red/purple liquids

Evaluation – Effectiveness

Monitor for:

• Clear, watery stool without solid material

• Adequate bowel cleansing for procedure

• Stable hydration and electrolytes

• No serious adverse effects