radpath_docnotes

Pathology

study of disease

Disease

Any abnormal disturbance of function/structure of human body as a result of injury

Pathogenesis

Sequence of events producing cellular changes

Manifestation

Observable changes from pathogenesis

Symptoms

PX perception of the disease; subjective

Sign

Objective manifestation that is detected by physician during examination

Syndrome

Group of sign and symptoms that characterized specific disturbance

Asymptomatic

Absence of symptoms

Etiology

Study of cause

Nosocomial

Disease acquired in hospital

Iatrogenic reaction

Adverse response to medical treatment

Idiopathic

Unknown cause

Acute

Quick onset & last short period

Chronic

Manifest more slowly, occur for long time

Sequelae

Lasting effect

Diagnosis

Identification of disease

Prognosis

Outcome of disease

Morphology

Study of structure of cell/tissue

Epidemiology

Study of how disease spread

Investigation of disease in large

Prevalence

# of cases found in given POPULATION

Incidence

# of new cases found in given PERIOD

Endemic

Disease of high prevalence in an area where given agent is commonly found

Epidemic

Appearance of disease in great numbers

Pandemic

Whole world

Mortality rate

Average # of deaths cause by particular disease in population

Morbidity

Incidence of sickness, sufficient to stop normal daily routine of individual

Genome

Chromosome in body (23 chromosomes)

Physical map

Determine physical location of particular gene in specific chromosome

Genetic map

Use to assign distance between genetic markers

Metaplasia

One cell type into another type

Dysplasia

Change in mature cell (size,shape,color)

Hypoxia

Decrease of oxygen

Result to cell injury and cell death

Abses

Collection of pus

Hematoma

Collection of blood

Homeostasis

Body’s normal internal resting state

Wound

Injury of soft part with rapture of skin

Bleeding

Result of blood vessel distraction

Benign

Well differentiated cell w/ control growth

Localize

Don’t spread; non-invasive

Malignant

Lost of control of differentiation; proliferation

Rapid growth

Spread and invades

Metastasis

Spread of malignant cell from primary toner

Seeding

Cancerous cell travels distant site

Lesion

Cellular charge and response to disease

Cancer

Malignancy

Carcinoma

Type of cancer

Congenital Disease

condition present at birth

genetic factors, environmental influence

Hereditary Disease

transmission from parent to child

Inflammatory Disease

body reaction to injury

inflammation

Degenerative Disease

tissue/organ deteriorate over time

due to aging

Metabolic disease

disturbance of normal physiologic function

affect body metabolism

chemical process food to energy

Traumatic disease

cause by physical injury or trauma

mechanical force

Neoplastic disease

new growth

abnormal cell growth