Module 6: Rheumatic Fever

Group A beta-hemolytic streptococci

Rheumatic fever is a complication of respiratory infection caused by what bacteria?

6 to 15 years old

Acute rheumatic fever is most common in what age range?

3 weeks

ARF occurs how many weeks after streptococcal infection if the upper respiratory system?

Polyarthritis

Which manifestation is caused by edema, inflammation, and effusions in joint tissue and is reversible and migratory?

Carditis

Which manifestation involves all the layers of the heart inclusive of the left-sided valves?

Apical systolic murmurs

What sounds are typically heard with mitral valve involvement?

Regurgitant murmur

What is a classic presentation of carditis?

Subcutaneous nodules

Which manifestation is characterized by small, non-tender swellings that persist indefinitely after the onset?

Erythema marginatum

Which manifestation is characterized by a transitory, nonpruritic, distinct erythematous macule with a clear center and a well demarcated border?

Sydenham’s chorea

Which manifestation is characterized by sudden, aimless, and irregular movements of the extremities that can last 5-15 weeks and is exaggerated with anxiety?

Previous RF, fever, arthralgia, prolonged PR interval, elevated CRP/ESR, leukocytosis

What are the minor criteria for rheumatic fever?

2 major, or 1 major and 2 minor

What are the criteria for a case to be considered highly probable?

M-chon titer

What is considered the definitive diagnosis for rheumatic heart disease?

Penicillin; erythromycin

What is the DOC for RHF? What can be given in cases of penicillin resistance?

Tranquilizer (Chlorpromazine, barbital)

What drug is given for patients experiencing chorea?

Aschoff bodies

What are the lesions in the connective tissues called?