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Define mass transport
Bulk movement of gases or liquids in one direction
What do mass transport systems help do
Maintain diffusion gradients and quickly move substances
Define haemoglobin
A globular protein which is an oxygen-carrying pigment found in red blood cells
Name two ways red blood cells maximise diffusion
Bioconcave for a high SA:Vol ratio, no nucleus for more oxygen storage
Describe how Hb has a quaternary structure
It is made up of four polypeptide chains
Define global proteins
Chains or subunits making up Hb, each with a prosthetic haem group
How are global subunits arranged
With disulphide bonds and a hydrophobic core
What features does Hb’s structure aid
The 3D structure and solubility
Describe how a prosthetic haem can bind to oxygen
The Iron ion in it can combine with oxygen to form oxyhemoglobin
How many oxygen molecules can a Hb carry
4
How many oxygen atoms can a Hb carry
8
Describe the function of Hb
Binding oxygen and transporting it from the lungs to the tissue, as it is not soluble
Give the other name for red blood cells
Erthrocytes
Define partial pressure
Pressure exerted by oxygen (concentration)
When is Hb saturated
When all its binding sites are filled
What does the oxygen disassociation curve show
The rate at which oxygen associated with Hb at partial pressures
Define affinity
How easily Hb binds and dissociates with oxygen
What does a high affinity mean for Hb
It can bind easily and dissociate slowly
What does a low affinity mean for Hb
It binds slowly and dissociates easily