DRUGS USED IN ADVANCED CARDIOVASCULAR LIFE SUPPORT

INDICATIONS for ADENOSINE

PSVT; recommended as a safe and potentially effective therapy in the initial management of stable undifferentiated regular monomorphic wide complex tachycardia

CONTRAINDICATIONS for ADENOSINE

use with caution if patient has asthma; may precipitate atrial fibrillation; poison-induced or drug induced tachycardia; second degree or third degree heart block; prolonged Q-T interval

ROUTE for ADENOSINE

IV BOLUS

PHARMACOLOGICAL EFFECTS for ADENOSINE

decrease in AV node conduction

does ADENOSINE increase or decrease HEART RATE

decrease

INDICATIONS for AMIODARONE

stable regular narrow-complex tachycardia to control rapid ventricular rate secondary to accessory pathway conduction in pre excited atrial arrhythmias

CONTRAINDICATIONS for AMIODARONE

prolonged Q-T interval

ROUTE for AMIODARONE

IV; IO

PHARMACOLOGICAL EFFECT FOR AMIODARONE

multichannel blocker( calcium, potassium ); inhibited ą- and b-adrenergic responses

does AMIODARONE increase or decrease HR?

decrease

INDICATIONS for ATROPINE SULFATE

acute symptomatic bradycardia

CONTRAINDICATIONS for ATROPINE SULFATE

sinus, atrial, and ventricular tachycardia, hypothermic bradycardia, infranodal AV block with wide QRS complexes

ROUTE for ATROPINE SULFATE

IV BOLUS; IO

PHARMACOLOGICAL EFFECTS OF ATROPINE SULFATE

increased heart rate; increased force of atrial contractions

INDICATIONS of DOPAMINE

hypotension with signs and symptoms of shock; second-line drug of symptomatic bradycardia

CONTRAINDICATIONS of DOPAMINE

use with caution in cariogenic shock with accompanying CHF

ROUTE for DOPAMINE

IV infusion

PHARMACOLOGICAL EFFECTS of DOPAMINE

increased renal and splenic flow at low doses; B-adrenergic effects at moderate doses; a-adrenergic effects at high doses

does DOPAMINE increase or decrease HR?

increase

INDICATIONS for EPINEPHRINE

cardiac arrest; VF;pulseless tachycardia;asystole;PEA;systomatic bradycardia; severe hypotension; anaphylaxis;severe allergic reaction

CONTRAINDICATIONS for EPINEPHRINE

VT and frequent PVCs

ROUTE for EPINEPHRINE

IV BOLUS;IO endotracheal use only if IV or IO cannot be established; IV infusion

PHARMACOLOGICAL EFFECTS of EPINEPHRINE

increased heart rate; increased force of atrial contractions;vasoconstriction;increased coronary perfusion pressure; increased myocardial irritability; increased myocardial O2 consumption

does EPINEPHRINE increased and decrease HR?

increase

INDICATIONS for ISOPROTERENOL

alternative when a bradyarythmia is unresponsive to or inappropriate for treatment with atropine, or as a temporizing measure while awaiting the availability of a pace-maker. Refractory torsade de pointes unresponsive to magnesium sulfate

CONTRAINDICATIONS for ISOPROTERENOL

cardiac arrest; VT; frequent PVCs

ROUTE for ISOPROTERENOL

IV infusions

PHARMACOLOGICAL EFFECTS for ISOPROTERENOL

increased heart rate; increased force of contractions; vasodilations

does ISOPROTERENOL increase or decrease HR?

increase

INDICATIONS for LIDOCAINE

second-line prophylactic antiarrhymthic therapy for monomorphic VT; lidocaine may be considered immediately after ROSC from cardiac arrest due to VF/pVT

CONTRAINDICATIONS for LIDOCAINE

signs of lidocaine toxicity; prophylactic use in acute MI

ROUTE for LIDOCAINE

IV BOLUS; IV INFUSION; IO; ENDOTRACHEAL

PHARMACOLOGICAL EFFECTS OF LIDOCAINE

increased electrical stimulation threshold; depressed ventricular electrical activity

INDICATIONS for PROPRANOLOL

suspected MI and unstable angina; SVTs

CONTRAINDICATIONS for PROPRANOLOL

bronchospactic disease; severe bradycardia; hypotension; second or third-degree heart block; cocaine-induced acute coronary syndrome

ROUTE for PROPRANOLOL

IV

PHARMACOLOGICAL EFFECTS for PROPRANOLOL

reduced heart rate; decreased stroke volume; decreased myocardial 02 consumption; increased LVEDP

INDICATIONS FOR VERAPAMIL/DILTIAZEM

alternative drug to terminate PSVT with narrow QRS complex, adequate blood pressure, and preserved left ventricular function; control ventricular rate in patients with atrial fibrillation or atrial flutter

CONTRAINDICATIONS for VERAPAMIL/DILTIAZEM

wide QRS-complex tachycardias of uncertain origins, Wolff-Parkinson-White syndrome, and AF; sick sinus syndrome, second-degree or third-degree block without pacemaker, concurrent IV administration with IV B blocker

ROUTE for VERAPAMIL/DILTIAZEM

IV BOLUS

PHARMACOLOGICAL EFFECTS on VERAPAMIL/DILTIAZEM

decreased sinoatrial node automaticity; slowed AV node conduction

does VERAPAMIL/DILTIAZEM increase or decrease HR?

decrease