Chapter 16 - Moving Proteins into Membranes and Organelles

Nuclear genes

________ take up most of the encoding go of mitochondrial and chloroplast proteins and they also use synthesized ribosomes which are imported into the organelles.

Glycoproteins

________ may be assisted in their folding by oligosaccharide side proteins, along with helping protect mature proteins from proteolysis, work as antigens and help with cell- cell adhesion.

Protein disulfide isomerase

________ (PDI) works as a catalyst for the formation and rearrangement of disfutile bonds in the ER lumen.

O

________- linked oligosaccharides are short and contain one to four sugar residues.

PTS1

They contain a C- terminal ________ targeting sequence and sometimes an N- terminal PTS2 targeting sequence, which arent cleaved after importing.

N terminal uptake

The ________ targeting sequence contains the information needed to target precursor proteins.

SecA protein

The ________ works as the driver for post- translational translocation through the inner membrane.

SRP

________ and the ________ receptor conduct the insertion of secretory protein in the translocon, and no additional energy is needed for this.

ER

The ________ binds to the signal recognition particle (SRP) which helps it turn into a nascent secretory protein, which targets the ribosome /nascent chain complex.

N

________- linked oligosaccharides contain two N- acetylglucosamine and three mannose.

negative bacteria

Completed proteins can be translocated through gram- ________, and the translocation takes the proteins through a translocon related to eukaryotic cells in the ER.

cytosolic receptor

If a protein is destined to the peroxisomal matrix, then they bind to a(n) ________ and they are directed to common import receptors along with translocation machinery along the peroxisomal membrane.

synthesization of peroximal proteins

The ________ occurs on cytosolic ribosomes and they are post- translationally incorporated into the organelle.