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what is E1
pyruvate dehydrogenase
what is E2?
dihydrolipoyl transacetyase
What is E3?
hihydrolipoyl dehydrogenase
what is the cofactor of E1?
TPP
what is the cofactor of E2?
lipoamide
what is the cofactor of E3
FAD+
what is the function of E1?
decarboylate pyruvate and attach it to itself to from hydroxyl ethyl TPP
what is the function of E2?
oxidize the ethyl group and transfer it onto CoA to make acetylCoA
what is the function of E3?
reoxidize E2 and return it to its original form