[4] Hypothalamic hormones + their effects on anterior pituitary hormones

All parts of 3-hormone process

Corticotropin-releasing hormone (CRH)

Hypothalamic hormone

Stimulates

• Adrenocorticotropic hormone (ACTH) secretion

Adrenocorticotropic hormone (ACTH)

Anterior pituitary hormone

Targets

• Adrenal cortex

Stimulates

• Glucocorticoid secretion

Gonadotropin-releasing hormone (GnRH)

Hypothalamic hormone

Stimulates

• Follicle-stimulating hormone (FSH) secretion

• Luteinizing hormone (LH) secretion

Follicle-stimulating hormone (FSH)

Anterior pituitary hormone

Targets

• Gonads

Promotes

• Gamete production

Stimulates

• Estrogen production (in females)

Luteinizing hormone (LH)

Anterior pituitary hormone

Targets

• Gonads

Responsible for

• Ovulation (in females)

• Corpus luteum formation (in females)

Stimulates

• Sex hormone secretion

• Testosterone secretion (in males)

Prolactin-inihibiting hormone (PIH) + dopamine

Hypothalamic hormone

Inhibits

• Prolactin (PRL) secretion

Prolactin (PRL)

Anterior pituitary hormone

Targets

• Mammary glands

• Other sex accessory organs

Promotes

• Milk production (lactating females)

• Various actions in other organs

Somatostatin

Hypothalamic hormone

Inhibits

• Growth hormone (GH) secretion

Growth hormone (GH)

Anterior pituitary hormone

Targets

• Most tissue

Promotes

• Protein synthesis + growth

• Lipolysis

• Increased blood glucose

Thyrotropin-releasing hormone (TRH)

Hypothalamic hormone

Stimulates

• Thyroid-stimulating hormone (TSH) secretion

Thyroid-stimulating hormone (TSH)

Anterior pituitary hormone

Targets

• Thyroid gland

Stimulates

• Thyroid hormone secretion

Growth hormone-releasing hormone (GHRH)

Hypothalamic hormone

Stimulates

• Growth hormone (GH) secretion