Proteins needed for DNA replication

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8 Terms

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DNA Polymerase I

Removes RNA primer and replaces it with newly synthesized DNA

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DNA Polymerase III

Main enzyme that adds nucleotides in the 5’-3’ direction

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Helicase

Opens the DNA helix by breaking hydrogen bonds between the nitrogenous bases

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Ligase

Seals the gaps between the Okazaki fragments to create one continuous DNA strand

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Primase

Synthesizes RNA primers neded to start replication

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Sliding Clamp

Helps to hold the DNA polymerase in place when nucleotides are being added

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Topoisomerase

Helps relieve the strain on DNA when unwinding by causing breaks, and then resealing the DNA

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Single-strand binding proteins (SSB)

Binds to single-stranded DNA to prevent DNA from rewinding back