4.4 regulation of metabolic pathways
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5 Terms
why regulate metabolic pathways
ensure the output of pathways meets biological demand
ensure that energy (ATP) is not wasted → by having opposing pathways run concomitantly in the same cell
how are the pathways regulated
enzyme concentration
enzyme activity
how does the enzyme activity regulate the pathway
end product → increase → inhibits activity of earlier enzyme → slow down / block pathway
how does the enzyme concentration regulate the pathway
end product → increase → inhibits synthesis of earlier enzymes → enzyme production decrease → little to no enzymes produced → slow down / block pathway
what does feedback regulation in cellular respiration do
cell’s catabolic and anabolic → demands change → feedback regulation: adjusts rate of respiration → to maximize efficiency
various inhibitors + activators → act at strategic points → regulate pace of glycolysis + citric acid cycle
acts close to the start of a pathway
Note 
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