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Carry out all chemical activities needed to sustain life
Cells and Tissues
are the building blocks of living things
Cells
are group of cells that are similar in structure and function
Tissues
Cells are not the
same
All ___ share general structure
cells
What are the three main regions of cells?
Nucleus, Cytoplasm, Plasma membrane
Control center of the cell
Nucleus
Contains genetic material (DNA)
Nucleus
Three regions of Nucleus
Nuclear membrane, Nucleolus, Chromatin
Barrier of nucleus
Nuclear Membrane
Consists of a double phospholipid membrane
Nuclear Membrane
Contain nuclear pores that allow for exchange of material with the rest of the cell
Nuclear Membrane
Nucleus contain one or more ___
Nucleoli
Sites of ribosome production
Nucleoli
Ribosomes then migrate to the cytoplasm through ___
nuclear pores
Composed of DNA and protein
Chromatin
Scattered throughout the nucleus
Chromatin
condenses to form chromosomes when the cell divides
Chromatin
Barrier for cell contents
Plasma Membrane
Double phospolipid layer
Plasma Membrane
what are the double phospholipid layer of the plasma membrane?
Hydrophilic heads and Hydrophobic tails
other materials in plasma membrane
Protein, Cholesterol, Glycoproteins
Finger-like projections that increase surface area for absorption
Microvili
Membrane junctions that are impermeable
Tight junctions
Membrane junctions that are anchoring junctions
Desmosomes
Membrane junctions that allow communication (commonly found in the heart and between embryonic cells)
Gap junctions
Material outside the nucleus and inside the plasma membrane
Cytoplasm
Fluid that suspends other elements
Cytosol
Metabolic machinery of the cell
Organelles
Non-functioning units
Inclusions
Made of protein and RNA & Sites of protein synthesis
Ribosomes
Found at two locations: Free in the cytoplasm & Attached to rough endoplasmic reticulum
Ribosomes
Fluid-filled tubules for carrying substances
Endoplasmic reticulum (ER)
Studded with ribosomes & Site where building materials of cellular membrane are formed
Rough Endoplasmic Reticulum
Functions in cholesterol synthesis and breakdown, fat metabolism, and detoxification of drugs
Smooth Endoplasmic Reticulum
Modifies and packages proteins and produces: Secretory vesicle, Cell membrane components & Lysosomes
Golgi apparatus
Contain enzymes that digest nonusable materials within the cell
Lysosomes
-Membranous sacs of oxidase enzymes
-Detoxify harmful substances
-Break down free radicals (highly reactive chemicals)
-Replicate by pinching in half
Peroxisomes
-“Powerhouses” of the cell
-Change shape continuously
-Carry out reactions where oxygen is used to break down food
-Provides ATP for cellular energy
Mitochondria
Network of protein structures that extend throughout the cytoplasm
Cytoskeleton
Provides the cell with an internal framework
Cytoskeleton
Type of Cytoskeleton where it is most involved in motility and cell shape changes. actin is one of it and it forms blue batlike network
Microfilaments
Type of Cytoskeleton where it is made of fibrous subunits. it helps form desmosomes and provide internal guy wires to resist pulling forces on the cell.
Intermediate filaments
Type of Cytoskeleton where it is made of repeating subunits of protein tubulin. it determines the overall shape of organelles. important for cell division.
Microtubules
Rod-shaped bodies made of microtubules
Centrioles
Direct formation of mitotic spindle during cell division
Centrioles
Not found in all cells & Used for movement
Cellular Projections
“eye lashes”- whiplike cellular extensions that moves materials across the cell surface
Cilia
___propels the cell. the only one of this in the body is the sperm
Flagellum
Cells that connect body parts
Fibroblast and Erythrocyte
Cells that cover and line body organs
Epithelial cell
cell that move organs and body parts
Skeletal muscle cell and Smooth muscle cell
cell that stores nutrients
fat cell
cell that fights disease
macrophage cell
cell that gathers information and controls body functions
nerve cell
cells of reproduction
Ovum and Sperm
movement of substance into and out of the cell
Membrane Transport
No energy is required to transfer
Passive transport
The cell must provide metabolic energy to transfer
Active transport
homogeneous mixture of two or more components
Solution
dissolving medium
Solvent
components in smaller quantities within a solution
Solutes
nucleoplasm and cytosol
Intracellular fluid
fluid on the exterior of the cell
Interstitial fluid
-The plasma membrane allows some materials to pass while excluding others
-This permeability includes movement into and out of the cell
Selective Permeability
-Particles tend to distribute themselves evenly within a solution
-Movement is from high concentration to low concentration, or down a concentration gradient
Diffusion: passive
Type of diffusion that’s an Unassisted process & Solutes are lipid-soluble materials or small enough to pass through membrane pores
Simple diffusion
Type of diffusion that’s simple diffusion of water
-Highly polar water easily crosses the plasma membrane
Osmosis
Type of diffusion where substances require a protein carrier for passive transport
Facilitated diffusion
-Water and solutes are forced through a membrane by fluid, or hydrostatic pressure
-A pressure gradient must exist
-Solute-containing fluid is pushed from a high pressure area to a lower pressure area
Filtration: passive
Transport substances that are unable to pass by diffusion
They may be too large
They may not be able to dissolve in the fat core of the membrane
They may have to move against a concentration gradient
Active Transport
-Amino acids, some sugars and ions are transported by ___
-ATP energizes protein carriers, and in most cases, moves substances against concentration gradients
Solute pumping: active
Exocytosis and Endocytosis
Bulk transport
-Moves materials out of the cell
-Material is carried in a membranous vesicle
-Vesicle migrates to plasma membrane
-Vesicle combines with plasma membrane
-Material is emptied to the outside
Exocytosis
Extracellular substances are engulfed by being enclosed in a membranous vesicle
Endocytosis
Type of endocytosis that’s cell eating
Phagocytosis
Type of endocytosis that’s cell drinking
Pinocytosis
major period of the cell where: Cell grows & carries on metabolic processes
Interphase
major period of the cell where: Cell replicates itself & Function is to produce more cells for growth and repair processes
Cell division
-Genetic material duplicated and readies a cell for division into two cells
- Occurs toward the end of interphase
- DNA uncoils and each side serves as a template
DNA Replication
Division of the nucleus & Results in the formation of two daughter nuclei
Mitosis
Division of the cytoplasm & Begins when mitosis is near completion & Results in the formation of two daughter cells
Cytokinesis
Stage of Mitosis where: No cell division occurs & The cell carries out normal metabolic activity and growth
Interphase
Stage of Mitosis where: First part of cell division & Centromeres migrate to the poles
Prophase
Stage of Mitosis where: Spindle from centromeres are attached to chromosomes that are aligned in the center of the cell
Metaphase
Stage of Mitosis where: Daughter chromosomes are pulled toward the poles & The cell begins to elongate
Anaphase:
Stage of Mitosis where: Daughter nuclei begin forming & A cleavage furrow (for cell division) begins to form
Telophase
DNA segment that carries a blueprint for building one protein
Gene
The Building materials for cells & Act as enzymes (biological catalysts)
Proteins
___is essential for protein synthesis
RNA
Transfers appropriate amino acids to the ribosome for building the protein
Transfer RNA /tRNA
Helps form the ribosomes where proteins are built
Ribosomal RNA/rRNA
Carries the instructions for building a protein from the nucleus to the ribosome
Messenger RNA/mRNA
Transfer of information from DNA’s base sequence to the complimentary base sequence of mRNA
Transcription
Base sequence of nucleic acid is translated to an amino acid sequence
Translation
___ are the building blocks of proteins
Amino acids
Groups of cells with similar structure and function
Tissues
Tissues found in Body coverings & Body linings
Epithelial Tissues
Tissues for: Protection, Absorption, Filtration, & Secretion
Glandular tissue
have no blood supply
Avascular