Preperation of Aspirin

how do you create aspirin/acetylsalicylic acid ?

u get salicylic acid react it w acetic anhydride and H3PO4; also making a byproduct acetic acid

is salicylic acid or acetylsalicylic acid more polar?

salicylic acid is more polar bc of the hydroxy group compared to an ester

ferric chloride/iron (III) chloride test is used to?

qualitatively detect the presence of the phenol functional group

what is an indicator that a phenol group is present?

the Fe(III) will form a highly colored iron-phenol complex

does acetylsalicylic acid contain a phenol functional group?

no

should you observe a color change when observing your product of when analyzing your final product?

no

what were the 3 Ferric Chloride tests and their purpose?

1. evaluate salicylic acid (control 1)

2. evaluate commercial aspirin (control 2)

3. evaluate your final product

positive test equals

purple color

negative test equals

no color change

how many peaks are shown in C13 NMR of salicylic acid?

7

how many new carbons are added after the creation of aspirin?

2

are the 2 carbonyl groups able to be differentiated in acetylsalicylic acid?

yes one is an ester and one is a carboxylic acid

how many peaks are shown in the C13 NMR of acetylsalicylic acid?

9