AP Bio DNA Scientists (history)

Griffith

Discovered transformation: shareable traits between bacteria (not plasmids)

Hershey and Chase

Used radioactive P to tag DNA, S to tag proteins, to see which truly expressed herditary information

Chargaff

Discovered 2 rules:

1. A = T, C = G

2. proportions varied between species but consistent within the same species

Franklin

Produced x-ray diffraction images, revealing helical structure, consistent width, and spacing of nucleotides

Wilkins

Worked with Franklin, showed Watson the x-ray

Watson and Crick

Constructed double-helix model with correct base pairing and antiparallel strands

Melson and Stahl

Discovered that semiconservative model was correct by centrifuging bacteria