adrenergic antagonists

what does “adrenergic antagonist” mean?

block/deactivate receptors in the SNS that use norepinephrine/epinephrine

what are the names of some non-selective adrenergic blocking agents?

amiodarone, carvediolol, labetalol → used to tx cardiac conditions like arrhythmias and HTN; work on ANY adrenergic receptors

what are adverse effects of non-selective adrenergic blocking agents?

fatigue, dizziness, NV, rhinitis, cough, heart failure, arrhythmias, hypotension → use with caution in those w COPD and asthma as they constrict bronchi making it harder to breathe

what are the names of some alpha 1 selective blocking agents?

doxazosin, prazosin, tamsulosin, terazosin → used for BPH, HTN

what are the names of some non-selective beta blocking agents?

propranolol, nadolol, nebivolol → used to tx HTN, migraines, prevent MI; block both beta 1 and beta 2 (work to decr cardiac output, use carefully in COPD/asthma)

what are the names of some beta 1 selective blocking agents?

atenolol, metoprolol → used to tx HTN, prevent MI, arrhythmias (safer choice for pts with COPD/asthma as these only affect beta 1 in heart)