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Apoptosis

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Biology

44 Terms

1

Apoptosis

The changes that occur within a cell as it undergoes programmed cell death, which is brought about by signals that trigger the activation of a cascade of suicide proteins in the cell destined to die.

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2

Biopsy

The removal and examination of tissue, cells, or fluids from the living body.

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3

Bone Scan

A test that detects areas of increased or decreased bone metabolism; a test is performed to identify abnormal processes involving the bone such as tumors, infection, or fractures.

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4

Cancer

A malignant tumor of potentially unlimited growth that expands locally and systemically.

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5

Cell Cycle

An ordered sequence of events in the life of a eukaryotic cell, from its origin in the division of a parent cell until its own division into two.

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6

Computed Tomography Scan (CT or CAT Scan)

A sectional 3-dimensional view of the body constructed by computed tomography.

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7

Diagnostic Imaging

Technologies that doctors use to look inside your body for clues about a medical condition; includes X-rays, CT scans, nuclear medicine scans, MRI scans and ultrasound.

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8

DNA Microarray

A microarray of immobilized single-stranded DNA fragments of known nucleotide sequence that is used especially in the identification and sequencing of DNA samples and in the analysis of gene expression (as in a cell or tissue).

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9

Magnetic Resonance Imaging (MRI)

A noninvasive diagnostic technique that produces computerized images of internal body tissues and is based on nuclear magnetic resonance of atoms within the body induced by the application of radio waves.

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10

Oncogene

A gene having the potential to cause a normal cell to become cancerous.

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11

Osteosarcoma

A cancer derived from bone or containing bone tissue.

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12

Proto-oncogene

A normal cellular gene corresponding to an oncogene; a gene with a potential to cause cancer but that requires some alteration to become an oncogene.

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13

Radiology

A branch of medicine concerned with the use of radiant energy (as X-rays or ultrasound) in the diagnosis and treatment of disease.

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14

Risk Factor

Something which increases risk or susceptibility.

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15

Tumor Suppressor Gene

A gene whose protein products inhibit cell division, thereby preventing uncontrolled cell growth (cancer).

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16

X-ray

To examine, treat, or photograph with X-rays.

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17

Cloning

Using a somatic or body cell from a multicellular organism to make one or more genetically identical individuals

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18

Gene therapy

The alteration of the genes of a person afflicted with a genetic disease

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19

In Vitro Fertilization

A procedure in which gametes are fertilized in a dish in the laboratory, and the resulting zygote is implanted in the uterus for development

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20

Preimplantation Genetic Diagnosis (PGD)

In assisted reproductive technology, the determination of genetic abnormalities in the embryo before it is transferred to the uterus

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21

Sex selection

Methods used to predetermine or diagnose the sex of an embryo for the purpose of selecting only those embryos of a particular sex for transplanting to the uterus of a woman

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22

Vector

An agent (as a plasmid or virus) that contains or carries modified genetic material and can be used to introduce extra genes into the genome of an organism

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23

Amniocentesis

A technique for determining genetic abnormalities in a fetus by the presence of certain chemicals or defective fetal cells in the amniotic fluid, obtained by aspiration from a needle inserted into the uterus

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24

Anneal

To be capable of combining with complementary nucleic acid by a process of heating and cooling

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25

Carrier screening

Indiscriminate examination of members of a population to detect heterozygotes for serious disorders

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26

Chorionic villus sampling (CVS)

A technique for diagnosing genetic and congenital defects in a fetus by removing and analyzing a sample of the fetal portion of the placenta

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27

Denaturation

In DNA, the separation of the two strands of the double helix.

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28

Gene

A discrete unit of hereditary information consisting of a specific nucleotide sequence of DNA

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29

Genetic counseling

A process of communication that deals with the occurrence or risk that a genetic disorder will occur in a family

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30

Genetic testing

The use of methods to determine if someone has a genetic disorder, will develop one, or is a carrier

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31

Genome

The complement of an organism’s genes; an organisms genetic material

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32

Genotype

The genetic makeup of an organism

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33

Karyotype

A display of the chromosome pairs of a cell arranged by size and shape

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34

Newborn screening

The analysis of a neonate's blood for metabolic or genetic disorders to prevent mental retardation, disability or death

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35

Phenotype

The physical and physiological traits of an organism

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36

Polymerase chain reaction (PCR)

A technique that involves copying short pieces of DNA and then making millions of copies in a short period

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37

Preimplantation Genetic Diagnosis (PGD)

In assisted reproductive technology, the determination of genetic abnormalities in the embryo before it is transferred to the uterus

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38

Primer

A short piece of DNA or RNA that is complementary to a section of template strand and acts as an attachment and starting point for the synthesis strand during DNA replication

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39

Restriction enzyme

A degradative enzyme that recognizes specific nucleotide sequences and cuts up DNA.

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40

Single nucleotide polymorphism (SNP)

One base-pair variation in the genome sequence

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41

Supernatant

The (usually) clear liquid left behind after a precipitate has been spun down to the bottom of a vessel by centrifugation

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42

Taq polymerase

A DNA synthesis enzyme that can withstand the high temperatures of PCR

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43

Thermal cycler

An instrument that automatically cycles through different temperatures used to complete PCR reactions

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44

Ultrasonography

A noninvasive technique involving the formation of a two-dimensional image used for the examination and measurement of internal body structures and the detection of bodily abnormalities

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