Enzymes - Week 2 Cell Bio

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Biological catalysts do what?

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1

Biological catalysts do what?

  • Increase the rate of aa reaction by lowering the activation energy

  • Forms transient complexes with substrate molecules

  • Lower activation energy

  • Changes only the rate at which equilibrium is achieved

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2

What law do enzymes obey?

The 2nd law of thermodynamics

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3

Can enzymes force unfavorable reactions?

Enzymes accelerate an energetically favorable reaction, BUT they cannot force unfavorable reactions to occur (only can make exergonic ones go)

  • Cells need to do just that to grow and divide

    • They build highly ordered and energy rich molecules from simple, small ones

    • This requires an INPUT of energy

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4

What is free energy?

The energy that can be harvested to do work or drive chemical reactions

  • The greater free energy, the greater the amount of disorder in the universe

  • Chemical reactions proceed only in a direction that leads to a loss of free energy

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